[tousled1]

Kriss,

Unfortunately DD A/C does have a cumulative effect. I was fortunate that I never actually got sick with it but I contribute that to taking the EMEND. I'm not saying I sailed through it by any means. I would have chemo and feel ok for about 2 days and then it was like walking into a brick wall! I got so exhausted all I could do was sleep, my counts dropped constantly and I was getting Neulasta shots for the white count and Procrit for the red counts. Just when I'd start feeling almost human again - WHAM, it was time for chemo again. Somehow we all get through it. We tend to be stronger than we think. I know that the Taxatere was worse for me than the A/C. The Decadron premed wound me up tighter than a kite and I had severe neuropathy with it. Just think you're half way done with the A/C. As for the headache just try laying down in a quiet, dark room. Also ice packs may help. Good luck to you.