Kriss,
After having the port in for a week or so, you probably won't even notice it anymore. Mine has been in for two years and I never think about it, except when it is being accessed. I did have Neulasta and had bone pain after each shot, so my guess is, if the first shot didn't bother you, you may not experience any side effects. I had one small period after first chemo--then no more. I have been on Lupron to keep me post-meno. Have just had to switch from 3 month shot to monthly because my estrodial level started to rise.
Up until this point my surgeon has not wanted me to have surgery to remove ovaries due to some other problems I have had. Those have all resolved now, so he gave me the green light for surgery if needed. I talked to my onc about it two weeks ago, and he prefers that I stay on Lupron if it continues to work. He got some information at San Antonio the Lupron may be more beneficial to HER2's than previously known. In studies now.
Good luck to you.
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