Hi Sue,
I am ER+PR+ and HER positive. I had bone mets, skin, lymph node, chest wall, and one spot on liver (March 06). Started in trial with Femara and 50/50% chance Lapatinib. Had partial response (skin, lymph node, chest wall - all gone) and progression in liver to 7 spots after 3 months. Still not sure if I got Lapatinib or not. Anyway, next we tried Gemzar and Herceptin (hard on the WBC counts). As of December, down to 3 spots on liver so small they are difficult to see after 4 months and bones are healing.
In my case another doctor wanted me to start with Taxol, Carbo, Herceptin combo. I guess everyone has different opinions and all cancers are different. No one knows for sure but it is good to be informed.
Now, switched to Faslodex and Herceptin. I also get a monthly dose of Zometa for bone mets. Will scan again in 3 months.
I am 50 years old and have had a hystorectomy.
I hope this helps, Carolyns
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