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Shonda.
It hasn't happened to me personally, but I have read of people having HER2- neg breast cancer with HER2+ mets.
HER2+ is now good because we have a drug for it. Spread, mets or stage IV are still not good, as far flung cancer in organs more useful than a breast are harder to deal with. You can't really have your lungs, liver, brain or bones removed.
Don't dwell on the stats, lot's of people here have had stage IV for a long time. Don't know if we've answered your question, best of luck. BB
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