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Sally,
As a precaution you may want to check if you have not become HER-2 positive so as not to delay a possible change in treatment.
The easiest,least intrusive, (besides biopsy) is the serum HER-2/neu test.
Also, if you find out that Tamoxifen is not working for you it should not be taken for a long time as some research has shown that keeping on Tamoxifen for about 3 months after resistance sets in can initiate HER-2 positive cancer.
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