HER2 Support Group Forums - View Single Post - Poor ten year prognosis for her2 t1No ....

JohnL · 12-15-2006, 02:39 AM

Had a quick look at this study. You are right, the data is drawn from individuals diagnosed 1986 - 1992. At this time I think it unlikely that early stage T1N0 patients were offered adjuvant chemo - and allowing for the small sample size the survival and relapse free rates are pretty much inline with other studies based upon patients treated only with surgery.

I think the purpose of the study is to underline the argument, 'Look what happens if we don't hit early stage HER2+ hard with everything we've got as soon as we can'. It's when you see figures like this you begin to appreciate how lucky we are to be living in 2006 not 1986.

Third generation chemo and Herceptin have changed DFS dramatically.

12-15-2006, 02:39 AM	#2
JohnL Member Join Date: Sep 2005 Location: London, England Posts: 24	Poor 10 year prognosis for T1N0 Had a quick look at this study. You are right, the data is drawn from individuals diagnosed 1986 - 1992. At this time I think it unlikely that early stage T1N0 patients were offered adjuvant chemo - and allowing for the small sample size the survival and relapse free rates are pretty much inline with other studies based upon patients treated only with surgery. I think the purpose of the study is to underline the argument, 'Look what happens if we don't hit early stage HER2+ hard with everything we've got as soon as we can'. It's when you see figures like this you begin to appreciate how lucky we are to be living in 2006 not 1986. Third generation chemo and Herceptin have changed DFS dramatically.