HER2 Support Group Forums - View Single Post - what type of mouthwash helps those with oral mucositis (sore mouth) from chemo

Lani · 12-01-2006, 01:19 PM

ABSTRACT: The effectiveness of commonly used mouthwashes for the prevention of chemotherapy-induced oral mucositis: a systematic review [European Journal of Cancer Care]
Daily chlorhexidine mouthwash is often recommended for preventing chemotherapy-induced oral mucositis. Povidone-iodine, NaCl 0.9%, water salt soda solution and chamomile mouthwash are also recommended. However, the effectiveness of these mouthwashes is unclear. Therefore, we performed a systematic review to assess the effectiveness of mouthwashes in preventing and ameliorating chemotherapy-induced oral mucositis. Based on study quality, three out of five randomized controlled trials were included in a meta-analysis. The results failed to detect any beneficial effects of chlorhexidine as compared with sterile water, or NaCl 0.9%. Patients complained about negative side-effects of chlorhexidine, including teeth discoloration and alteration of taste in two of the five studies on chlorhexidine. The severity of oral mucositis was shown to be reduced by 30% using a povidone-iodine mouthwash as compared with sterile water in a single randomized controlled trial. These results do not support the use of chlorhexidine mouthwash to prevent oral mucositis.

povidone-iodine is Betadine (sold over the counter) I was unaware it was safe to use orally

12-01-2006, 01:19 PM	#1
Lani Senior Member Join Date: Mar 2006 Posts: 4,782	what type of mouthwash helps those with oral mucositis (sore mouth) from chemo ABSTRACT: The effectiveness of commonly used mouthwashes for the prevention of chemotherapy-induced oral mucositis: a systematic review [European Journal of Cancer Care] Daily chlorhexidine mouthwash is often recommended for preventing chemotherapy-induced oral mucositis. Povidone-iodine, NaCl 0.9%, water salt soda solution and chamomile mouthwash are also recommended. However, the effectiveness of these mouthwashes is unclear. Therefore, we performed a systematic review to assess the effectiveness of mouthwashes in preventing and ameliorating chemotherapy-induced oral mucositis. Based on study quality, three out of five randomized controlled trials were included in a meta-analysis. The results failed to detect any beneficial effects of chlorhexidine as compared with sterile water, or NaCl 0.9%. Patients complained about negative side-effects of chlorhexidine, including teeth discoloration and alteration of taste in two of the five studies on chlorhexidine. The severity of oral mucositis was shown to be reduced by 30% using a povidone-iodine mouthwash as compared with sterile water in a single randomized controlled trial. These results do not support the use of chlorhexidine mouthwash to prevent oral mucositis. povidone-iodine is Betadine (sold over the counter) I was unaware it was safe to use orally