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Old 11-30-2006, 06:16 AM   #3
Shell
Senior Member
 
Join Date: Sep 2005
Location: Philadelphia
Posts: 301
Cathy-

I was in the original trial w/ xeloda/tykerb - I received only xeloda at first, but it really kicked back my lung mets...eventually tykerb was added, but it had been about a 15 months on xeloda by that time, and side effects were getting bad for me, and I wasn't as stable as I was so I've since switched.

But, obviously you will want to keep your onc advised of ALL side effects - the diarrhea and the H/F syndrome are the biggies. www.xeloda.com has a great website, and they list lots of ideas. I only saw my doc every 6 or 12 weeks (remember, it's just pills you're taking), so I used the treatment diary to track my symptoms and to keep track that I was remembering to take all the pills! I would usually email my onc's nurse once a week or two with updates. I had cat scans and echo every 6 or 12 weeks.

When I added the tykerb to the mix, I was extremely fatigued for a few days, but eventually got back to my normal state of regular fatigue...

I used udder cream, and found that to be the best for me - good luck with things!!

When did you have the avastin and what did you have it with? I am having it now with doxil, and am curious how long you were on it and what scans showed during that period for you...

Take care,
Shell
__________________
Shell

init diag 3/17/03-stage IIIC
ER-/PR-/HER2+++
CET x4 neo-adjuvant
lump & SNB 8/03
CET x2
radiation and herceptin/navelbine 11-03-1/04
1st reoccur to lymph nodes 8/04
complete axillary dissection 12/04
herceptin/taxotere til progression (lungs) 3/05
xeloda w/out lapatinib trial 6/05
lapatinib/tykerb added 4/06
ended trial 8/06 due to progression
doxil / avastin 11/06-12/06 - wasn't working
navelbine/herceptin/avastin 12/06/3/07 - progression
gemzar/carboplatin/tykerb 4/07
mri shows extensive mets to bone in pelvic area 6/07
switched to abraxane (3 on/1 off) + tykerb 6/07
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