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Rising 27.29 tumor marker levels
I was interested to hear people's experiences with their tumor marker levels rising after starting tamoxifen. My numbers have always been very low, but the trend has been for my numbers to rise. A year ago my 27.29 level was 7, then in June was up to 16, that's what prompted new tests and mets dx. Saw my onc yesterday and I am very concerned that my tumor marker jumped from that 16 five months ago to 59 as of last week. My onc said it is normal for the level to rise after starting tamoxifen, but I was freaked and didn't ask more questions. He's trying to get me in for a pet/ct this week. Thanks for any thoughts, input on this.
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Liz
3/05 Initial dx invasive dc 2 cm lump, age 39
lumpectomy & 3 of 5 nodes +, ER+/PR+, Her2+++
alternative chemo 5/05-7/05, rad 8/05-10/05
7/06 dx mets to vertebrae, pelvis & chest lymph nodes
8/06 - 10/06 tamoxifen, herceptin, oophorectomy & zometa
11/06 PET/CT showed continued bone mets, new spot on liver
12/06 began taxotere/herceptin 1x/3 weeks,
2/07 - 2-08 NED!
3/08 progression, start taxol/herceptin weekly, monthly zometa
8/08 start ai & herceptin
12/08 - progression, start weekly navelbine/herceptin thru 6/09 & monthly zometa
7/09 - PET/CT showed improvement in spine, but 2-3 lymph nodes in chest became active
9/09 - 11/09 - weekly abraxane/herceptin
12/09 - PET/CT - chest lymph nodes resolved, progression in spine & pelvis
2/10 - 6/10 - start tykerb/xeloda, progession in spine & pelvis
7/10 - start taxotere/carboplatin/herceptin
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