[Margerie]

Michelle,Yes, good question. My onc said off-label use should reflect current studies, which is either tykerb + herceptin or tykerb + xeloda. I am electing a second year of herceptin (starts mid-Jan), so if we add tykerb in March, I will have both for 9 months. Assuming the ole heart hangs in, has been fine so far. Maybe go another 3 months to make a year of Tykerb. But that herceptin is going to break the bank. We have had to pay our HUGE deductible three years in a row- not too hot on 4 years. Don't think I want to try xeloda at Stage 3.

Let me know what your onc says.