[Lani]

I see you are not her2+(no bigee!), but just to let you know so far I have found what seem to be the only two papers specifically discussing whether her2 tumors recur more frequently locally than others after radiation therapy--they do not appear to.

Hard to find similar papers on LVI, although the general assumption is that if the tumor is aggressive enough to have shown signs of "escape" already it might be more likely to recur somewhere else in the same breast. THAT might theoretically be a reason to have whole breast irradiation (external beam) rather than partial breast irradiation (mammosite, other brachytherapy techniques or external APBI),but again, I haven't yet found a paper that
discusses that specifically.

Let me know if anyone else has. Hope this helps!

ALSO whole breast radiation treats the bottom-most lymph nodes in the armpit even without a lymph node boost from what I understand--which is probably why they only let node negative patients into most APBI trials