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Old 11-13-2006, 05:32 AM   #5
tousled1
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Join Date: Feb 2006
Location: Acworth, GA
Posts: 2,104
Val,

I don't know why my oncologist chose the neo-adjunct chemo that she did. At that time I was very uninformed and still in a state of shock. I just went along with what she decided. The only thing I knew was that I did not want surgery first -- too close to the Holidays (stupid reasoning??). I can tell you that my onc did state that with the A/C and then Taxatore there was good results in tumor shrinkage. I can attest to that -- the tumor did indeed shrink but I still opted for the bilateral mastectomy. I didn't want to have to go through surgery again if I had recurrence. Another factor may be that I was 57 at the time of my diagnosis and we already knew that there was lymph node involvement. I had lymph node needle aspiration biopsy done at time of initial biopsy. Other factors that were unfavorable in my biopsy report were Ploidy/DNA index (Aneuploid/1.61) and S-phase 24.2%. Like Lani said, it's like comparing apples and oranges. The most important thing in any treatment plan is the end result.
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Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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