Thread: omega 2, 6, 9 ?
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Old 10-03-2006, 05:33 PM   #4
heblaj01
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Join Date: Apr 2006
Posts: 543
To the extensive info supplied by RB on various fats I would like to add this point on the different mode of absorption of of Omega-3 & Omega-6&-9 fats.

Omega-6 &-9 being part of the family of fats called Medium Chain Fatty Acids (MCFA) are absorbed quickly & directly from gut to liver.

Omega-3's are part of Long Chain Fatty Acids (LCFA) whose absorption is more complex & involves enzymes such as lipase as well as bile. While these fats may not be so easily absorbed they are not going initially to the liver but circulate through the the lymphatic system.
As a result they tend to have a wider body distribution & to stay longer in the body before being metabolized or degraded in the liver.
This may explain in part the effectiveness of Omega-3's as anti-inflammation supplements & in mice as actve agents in regressing metastatic lymph nodes.

As RB noted none of the usual sources of Omega-3 or 6 or 9 are pure.
They are mixtures with a preponderance of one (GLA sources are an exception with less than 50% content).
There are now available two pure sources of the Omega-3's : pure EPA & pure DHA. However I am not aware of research studies combining these two pure supplements as in the numerous studies dealing with Omega-3 fish oil (which may contain up to 60% of combined EPA/DHA).
So their combined efficacy still needs to be demonstrated.
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