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At ASCO 2006 I personally went to the presentation on the benefit of adding a taxane after 4 dense dose AC treatments.
A taxane is most beneficial to those who are Her2 positive (regardless of hormone status - and this part was stressed over and over again because....) a taxane was shown to be of NO benefit to those who were only hormone positive (and Her2 negative). Adding a taxane was also of great benefit to triple negatives.
If I had a tumor that was Her2+ and over 1cm - even with negative nodes, I would insist on 4 taxol treatments after the AC adding in the Herceptin with the taxol treatments and then Herceptin out to a year. It is that much more beneficial. Check it out under the ASCO 2006 site (when I get home late tonight, I will look it up and let you know the abstract number).
Kindest regards
Becky
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