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Hello Frank, how nice to hear from you again, although sorry to hear Evelyn has to start a new regimen. However, Navelbine is usually quite effective with Herceptin, in my experience. My first recurrence, although I don't have IBC, did include some skin invlovement in the form of small tumors just under the skin in the scar line; with my very first infusion I felt a general pain in the whole left side where I'd had my mastectomy, and also sharp pain in my shoulder blade and arm. By the second or third day those skin nodules were reddened and I could feel small shooting pains, where before they had been entirely painless. Also, a mole just above the scar line became reddened and the skin around it actually blistered, later peeling. By the third week(I was on weekly infusions) the skin nodules were gone, the mole had returned to normal, and I had no more pain. But I did develop stomach issues while on Navelbine, and began Prilosec, which I stilll take daily even though not on Navelbine at this time.
I think Evelyn's response is encouraging! Please keep us posted, and take care.
<3 Lolly
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