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Old 08-29-2006, 06:44 AM   #6
R.B.
Senior Member
 
Join Date: Mar 2006
Posts: 1,843
Yes omega three and six have roles here through the eicosanoid.

Omega three and six each have their own families of thromboxanes.

It is Not an area I have specifically read up on, but IF it follows the pattern in very genereral terms omega six will provide the emergency high power functions and omega three the gentler long term repair solutions.


RB




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Thromboxane is a member of the family of lipids known as eicosanoids. It is produced in platelets by thromboxane-A synthase, which is produced from the endoperoxides by the cyclooxygenase (COX) enzyme from arachidonic acid.
Enzymes and substrates associated with thromoboxane and prostacyclin synthesis.
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Enzymes and substrates associated with thromoboxane and prostacyclin synthesis.

Thromboxane is a vasoconstrictor and a potent hypertensive agent, and it facilitates the clumping of platelets. It is in homeostatic balance in the circulatory system with prostacyclin, a related compound. The widely used drug aspirin acts by inhibiting the ability of the COX enzyme to synthesize the precursors of thromboxane within platelets.

Thromboxane is named for its role in clot formation (thrombosis). Thromboxane A2 (TXA2), produced by activated platelets, has prothrombotic properties, stimulating activiation of new platelets as well as increasing platelet aggregation. Platelet aggregation is achieved by mediating expression of the glycoprotein complex GP IIb/IIIa in the cell membrane of platelets. Circulating fibrinogen binds these receptors on adjacent platelets, further strengthening the clot.

It is believed that the vasoconstriction caused by thromboxanes plays a role in Prinzmetal's angina.
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