[RobinP]

Unfortunately, there no studies on Herceptin alone as adjuvant therapy in early stage disease. However, there are studies done on the mets population that indicates that chemo plus Herceptin is more effective than chemotherapy alone. So for right now that standard of care for her2 positive bc is Herceptin and chemo, anything less would be sub standard care. Personally, I would have a hard time doing a sub standard treatment for an aggressive bc like her2 positive that was hormonal negative. Not to alarm you but, breast cancer that is er,pr negative is usually very aggressive, growing faster and spreading readily. You might look at breastcancer.org and look up hormonal negative in the search in order to see just how effective chemotherapy is in particularly hormonal negative bc.