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Forum: Articles of Interest

02-21-2007, 10:31 AM

Replies: 13

Gene Profiling Predicts Resistance To Breast Cancer Drug Herceptin

Views: 3,456

Posted By Lani

hot-off-the press: her2+ breast cancer recurrence after vaccination

with her2 vaccines in rats seems to be due to "survival of the fittest" of clonogenic group of cells which have epigenetically silenced her2 (methylation of gene which essentially hides it from being...

Forum: Articles of Interest

02-20-2007, 01:01 PM

Replies: 13

Gene Profiling Predicts Resistance To Breast Cancer Drug Herceptin

Views: 3,456

Posted By Lani

just read this today--lapatinib tends to work on EGFR, IGFR simultaneously

and reverse herceptin resistance. It was done on SKBr3 (her2+er-) but in its discussion opined that triple positive bc would probably need treatment with an her2inhibitor, IGFR inhibitor and ER...

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