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Search: Posts Made By: Nguyen
Forum: Articles of Interest 10-10-2020, 04:35 PM
Replies: 0
Views: 87
Posted By Nguyen
Clinical implications of prospectivegenomic profiling of metastatic breastcancer pati

https://breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-020-01328-0


Clinical implications of prospective genomic profiling of metastatic breast cancer patients

Sherene Loi...
Forum: Articles of Interest 10-08-2020, 12:52 PM
Replies: 0
Views: 44
Posted By Nguyen
Novel targeted therapies for metastatic breast cancer

A short summary of "newer" (since trastuzumab) non-chemo agents across breast cancer types.

http://atm.amegroups.com/article/view/38534/html

They forgot to add Trastuzumab duocarmazine...
Forum: her2group 10-04-2020, 08:49 AM
Replies: 1
Views: 75
Posted By Nguyen
Re: Is there problem with the site?

The problem is fixed. Thanks.
Forum: Articles of Interest 10-04-2020, 08:47 AM
Replies: 0
Views: 54
Posted By Nguyen
Breast cancer and covid

Since the beginning I have been wondering about cancer and covid, but afraid to search for data. Much of the information on this are very preliminary and based on very small data set.
...
Forum: her2group 10-03-2020, 08:44 AM
Replies: 1
Views: 75
Posted By Nguyen
Is there problem with the site?

Hello,

Is there problem with the site, particularly posting to sections "Article of Interest" and "Herceptin/Tykerb"? Thanks.

Nguyen
Forum: Articles of Interest 10-02-2020, 09:01 AM
Replies: 0
Views: 42
Posted By Nguyen
This scientist made a Google Doc to educate the public about airborne coronavirus tra

I'm sorry for this off topic post, but once in a while I run into a highly reputable and well organized covid info.

Nguyen
...
Forum: Articles of Interest 09-21-2020, 01:54 PM
Replies: 0
Views: 119
Posted By Nguyen
First New Drug in Years Reduces Recurrence in High-risk Hormone Receptor Positive Ear

I usually post only Her2Positive and late Met articles. But I was caught by the phrase “…first time in 20 years…” in the articles below so here we are. By the way, my wife Her2+++ is taking...
Forum: Articles of Interest 09-19-2020, 09:31 AM
Replies: 0
Views: 68
Posted By Nguyen
Biomarkers in Breast Cancer: An Integrated Analysis of Comprehensive Genomic Profilin

Biomarkers in Breast Cancer: An Integrated Analysis of Comprehensive Genomic Profiling and PD‐L1 Immunohistochemistry Biomarkers in 312 Patients with Breast Cancer
...
Forum: Articles of Interest 09-19-2020, 09:30 AM
Replies: 0
Views: 63
Posted By Nguyen
Circulating tumour DNA analysis to direct therapy in advanced breast cancer

I have been waiting for significant data on this subject (“liquid biopsy”) for 2 decades now. Even with many tumor sites, it’s always risky to get my wife biopsy. Due to tumor heterogeneity one can...
Forum: Articles of Interest 09-17-2020, 04:43 PM
Replies: 0
Views: 77
Posted By Nguyen
“…evaluating palbociclib (CDK4/6) treatment outcome …”

https://www.biospace.com/article/releases/clinical-cancer-research-publishes-results-supporting-divitum-as-a-technology-for-early-evaluation-of-metastatic-breast-cancer-treatment/
...
Forum: Articles of Interest 09-15-2020, 12:50 PM
Replies: 4
Views: 192
Posted By Nguyen
Re: Rapid Breast Cancer Disease Progression Following Cyclin Dependent Kinase 4 and 6

Abemaciclib with continuous dosing v.s 3 weeks on 1 off for the others CDK4/6, abemaciclib does have less severe neutropenia. Unfortunately, we still have to temporary hold treatment due to low...
Forum: Articles of Interest 09-09-2020, 09:44 AM
Replies: 0
Views: 99
Posted By Nguyen
Latest Overview of the Cyclin-Dependent Kinases 4/6 Inhibitors...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856891/

Don’t remember if I posted this before, can’t believe I am hogging this section (articles of interest), please feel free to tell me to stop. ...
Forum: Articles of Interest 09-09-2020, 08:22 AM
Replies: 4
Views: 192
Posted By Nguyen
Rapid Breast Cancer Disease Progression Following Cyclin Dependent Kinase 4 and 6 Inh

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559961/

Although an extremely small sample size (4), it is scary to read for us at the moment. I haven't been able to find (yet) more study one way...
Forum: Articles of Interest 09-09-2020, 08:13 AM
Replies: 0
Views: 102
Posted By Nguyen
CDK4/6 inhibitors: The mechanism of action may not be as simple as once thought

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039233/

Nguyen
Forum: Articles of Interest 08-09-2020, 09:05 AM
Replies: 0
Views: 329
Posted By Nguyen
Combination Strategies ...Immunotherapy

Combination Immunotherapy Strategies in Breast Cancer

https://link.springer.com/content/pdf/10.1007/s12609-019-00333-3.pdf

Combination Strategies of Checkpoint Immunotherapy in Metastatic...
Forum: Articles of Interest 07-19-2020, 03:22 PM
Replies: 0
Views: 415
Posted By Nguyen
Six distinct "types" of COVID-19 identified

A bit "dramatized title" in the simplified version, note information have not been through peer reviewed process.

Nguyen

The simplified version:
...
Forum: Articles of Interest 07-17-2020, 07:01 PM
Replies: 0
Views: 276
Posted By Nguyen
Metastatic HER2+ Breast Cancer Treatment Must Move to Personalized Approach

https://www.onclive.com/view/metastatic-her2-breast-cancer-treatment-must-move-to-personalized-approach
Forum: Articles of Interest 07-17-2020, 06:49 PM
Replies: 0
Views: 262
Posted By Nguyen
Leveraging CDK4/6 Inhibitors in Earlier Settings to Boost Outcomes in HR+ Breast Canc

https://www.onclive.com/view/leveraging-cdk4-6-inhibitors-in-the-earlier-settings-to-boost-outcomes-in-hr-breast-cancer
Forum: Articles of Interest 07-17-2020, 01:02 PM
Replies: 0
Views: 256
Posted By Nguyen
Risk of early progression according to circulating ESR1 mutation...

https://breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-020-01290-x

Abstract
Background

Endocrine therapy is recommended as a first-line treatment for hormone...
Forum: her2group 07-11-2020, 08:52 AM
Replies: 1
Views: 599
Posted By Nguyen
Re: Abemaciclib plus trastuzumab with or without fulvestrant versus trastuzumab plus

Thanks Lani, somehow I missed this. This info has immediate use for us in our upcoming treatment decision, assuming we can get it via off-label used for her2 positive.

Nguyen
Forum: Articles of Interest 06-25-2020, 08:28 PM
Replies: 0
Views: 556
Posted By Nguyen
Hopefully this will be another weapon for us in the fight.

https://www.icr.ac.uk/news-archive/new-class-of-precision-medicine-strips-cancer-of-its-dna-defences


https://ascopubs.org/doi/10.1200/JCO.19.02404
Forum: Articles of Interest 06-25-2020, 07:26 AM
Replies: 0
Views: 304
Posted By Nguyen
Cardiac monitoring in HER2-positive patients

Cardiac monitoring in HER2-positive patients on trastuzumab treatment: A review and implications for clinical practice
...
Forum: Articles of Interest 06-11-2020, 09:58 AM
Replies: 0
Views: 407
Posted By Nguyen
6/2020:American Cancer Society Guideline for Diet and Physical Activity for cancer pr

If memory serves, main difference with past recommendations is double the amount of daily exercise and intensity.

Nguyen

https://acsjournals.onlinelibrary.wiley.com/doi/full/10.3322/caac.21591...
Forum: Articles of Interest 06-08-2020, 07:34 AM
Replies: 0
Views: 328
Posted By Nguyen
A couple of articles on current immunotherapy for her2 positive BC

Useful background info, albeit a bit long and moderately technical, note "current" <= 03/2020.

Nguyen

https://www.nature.com/articles/s41523-020-0153-3
...
Forum: Articles of Interest 06-05-2020, 09:28 AM
Replies: 1
Views: 559
Posted By Nguyen
Re: Treatment After Progression on CDK 4/6i in mBC

Therapy After Cyclin-Dependent Kinase Inhibition in Metastatic
Hormone Receptor-Positive Breast Cancer: Resistance
Mechanisms and Novel Treatment Strategies
...
Showing results 1 to 25 of 264

 
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