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Search: Posts Made By: Lani
Forum: her2group 08-23-2013, 05:01 PM
Replies: 16
Views: 4,041
Posted By Lani
Re: and what have your HERs been up to? Scientist ID many more interactions of her1-4

http://www.breakthrough.org.uk/news/all-news/pertuzumab-rejected-nice-breakthrough-responds
Forum: her2group 08-23-2013, 03:51 PM
Replies: 16
Views: 4,041
Posted By Lani
Re: and what have your HERs been up to? Scientist ID many more interactions of her1-4

Glad you found this old post of mine.

The efficacy of pertuzumab speaks to the importance of her3 in her2+ breast cancer

There are so many to thank for developing, testing, manufacturing, even...
Forum: her2group 08-22-2013, 09:50 AM
Replies: 0
Views: 1,252
Posted By Lani
Thumbs up hope for those who receive Whole brain radiation therapy

late cognitive defects have been associated with WBR--although early research and only in lab animals, this is the first paper I have seen showing any evidence of improvement with treatment

...
Forum: her2group 08-21-2013, 09:39 AM
Replies: 2
Views: 1,616
Posted By Lani
more on the "GOLDILOCKS" of herceptin treatment--6 months not as good as 12

before I reported that 2 years was determined not to be better than 1 year

Here is the opposite trial-- and 6 months was not better than 12, except in terms of cardiac toxicity, and that...
Forum: Herceptin / Tykerb 08-15-2013, 10:36 PM
Replies: 689
Views: 473,430
Posted By Lani
Re: Please post your two cents on Herceptin "side effects" real or perceived!

RAZm sometimes side effects happen long after a treatment. Then it is hard to attribute it to something you are no longer on.

I am not aware if you were premenopausal prior to the chemo, but one...
Forum: her2group 08-14-2013, 07:26 PM
Replies: 0
Views: 2,271
Posted By Lani
Lightbulb for those running out of options, having failed combinations of antiher2 treatments

th culprit could be a Pi3K mutation. This may possibly help give an indication of what clinical trials may be more or less likely to get around this problem. caveat: this is based on a mouse model...
Forum: her2group 08-13-2013, 01:21 PM
Replies: 3
Views: 2,266
Posted By Lani
new review article on treatment of her2+ breast cancer by Dr Pegram

Dr Pegram worked hand-in-hand with Dr Slamon for decades before moving to Miami and now Stanford.

He hosts an large number of panel discussions and poster discussion seions on her2+ bc at SABCS,...
Forum: her2group 08-09-2013, 09:00 PM
Replies: 0
Views: 1,573
Posted By Lani
Thumbs up new strategy combining nanoformulatn, herceptin-immunoconjugate wth IL2, anti-lamenin

(protein necessary for tumors to form new blood vessels) against her2+ breast cancer cells, throwing a three-pronged targetted punch with a Trojan horse entry. They seem to be throwing in everything...
Forum: her2group 08-06-2013, 08:02 PM
Replies: 3
Views: 1,482
Posted By Lani
Thumbs up Remarkable hopeful news on preventing, treating bc brain mets

few things have been shown to prevent bc spread to the brain or the mets taking hold there.

Dr. Steeg has made this her special field of interest

It is only in an animal model, but the...
Forum: her2group 08-02-2013, 11:43 AM
Replies: 10
Views: 3,383
Posted By Lani
Re: Anyone else dx with RA since ending treatment?

one theory of how chemo works in breast cancer is by decreasing the number of T regulatory cells so that the cancer cannot evade the immune system so well (there are a lot of more gentle ways to do...
Forum: her2group 07-23-2013, 11:48 PM
Replies: 6
Views: 2,335
Posted By Lani
Thumbs up open access article on the latest and greatest in treatment for her2+ breast cancer

highly recommended--use the chocolate, whipped cream and cherries technique I have previously recommended to read it or ask me specific questions about phrases you do not understand...
...
Forum: her2group 07-22-2013, 12:49 AM
Replies: 6
Views: 1,678
Posted By Lani
Re: question for Hawaiian/Australian/other coaster members

a quick review of recent literature found the folowing:

Apply a topical gel with xylocaine--the calcium channel blocker stops the jellyfish toxin's effect (just published this year)

there seems...
Forum: her2group 07-22-2013, 12:45 AM
Replies: 6
Views: 2,430
Posted By Lani
Re: once again, with feeling.... yet another study confirms ER+her2+ breast cancer as

PCR=pathological complete response which refers to the fact that when they biopsy where a tumor had been AFTER neoadjuvant (presurgery) chemotherapy, they cannot find any tumor left
Forum: her2group 07-21-2013, 12:55 AM
Replies: 17
Views: 5,346
Posted By Lani
Re: Neuropathy, Shingles or pinched nerve

Why see a podiatrist--who is not an MD and doesn't go to medical school--when you can see an orthopaedic surgeon who specializes in foot and ankle. They are trained to differentiate whether the pain...
Forum: her2group 07-20-2013, 01:53 AM
Replies: 23
Views: 5,620
Posted By Lani
Re: Why do I read posts saying hercept not working

AM travelling tomorrow and packing tonight, but let me try to answer a few questions.
NO--we don't want the puppy to get out. Chemotherapy is like carpet bombing (targetted therapy with monoclonal...
Forum: her2group 07-19-2013, 01:28 PM
Replies: 6
Views: 1,678
Posted By Lani
Question question for Hawaiian/Australian/other coaster members

this one has me stumped-- not much in PubMed'smedical literature or google, so I will see if anyone has experience

I have been asked what treatment would be for a jellyfish sting to an arm which...
Forum: her2group 07-19-2013, 01:42 AM
Replies: 23
Views: 5,620
Posted By Lani
Re: Why do I read posts saying hercept not working

Upon reading your other posts it seems you are an early breast cancer survivor, not a Stage IV.

You seem to be hounded by the thought that herceptin may not have taken care of your cancer, that...
Forum: her2group 07-19-2013, 01:12 AM
Replies: 23
Views: 5,620
Posted By Lani
Re: Why do I read posts saying hercept not working

It often seems that posts can be inaccurate (noone is being graded here and there are no pop-quizzes, just people trying to help one another!)...by saying herceptin is not working they may mean that...
Forum: her2group 07-10-2013, 08:22 AM
Replies: 0
Views: 1,304
Posted By Lani
Exclamation WARNING--clinical trial finds acetyl L-carnitine supplement not only doesn't protect

against taxane-caused peripheral neuropathy, it may even make it worse!!



Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy...
Forum: her2group 07-09-2013, 12:51 AM
Replies: 17
Views: 5,346
Posted By Lani
Question Re: Neuropathy, Shingles or pinched nerve

Is the pain under your arch toward the heel (plantar fasciitis) or under the area that hurts when you wear high-heels (metatarsal heads) and if so, is it between your 3rd and 4th toes, This could be...
Forum: her2group 07-08-2013, 04:12 PM
Replies: 42
Views: 7,146
Posted By Lani
Re: And The Winner Is...

not only shouldn't you have a procedure during a long holiday weekend you should be extra sure it is not the July 4 holiday weekend because all the new interns and residents start on July 1 and may...
Forum: her2group 07-07-2013, 06:35 PM
Replies: 7
Views: 1,842
Posted By Lani
Thumbs up cruciferous vegetable (broccoli, brussel sprouts) component PREVENTS brain mets,

decreases growth of brain mets and prolongs survival in mice given human her2+ breast cancer cell injection

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0067278
Forum: Inflammatory Breast Cancer 07-06-2013, 10:44 AM
Replies: 1
Views: 11,635
Posted By Lani
Thumbs up hydrophilic status may increase progression-free survival in IBC

I mean't hydrophilic statins, but don't know how to correct the subject line!!!


Br J Cancer. 2013 Jul 2. doi: 10.1038/bjc.2013.342. [Epub ahead of print]
Statin use in primary inflammatory...
Forum: her2group 07-06-2013, 10:11 AM
Replies: 0
Views: 2,168
Posted By Lani
garlic oil helps boost White blood cells during chemo/radiation therapy (in mice)

haven't read full article yet, but thought this might be worth posting already

Garlic Oil May Ease Cancer Tx Side Effects

Garlic oil may reduce hematologic adverse effects of chemotherapy and...
Forum: her2group 06-30-2013, 02:48 AM
Replies: 23
Views: 6,028
Posted By Lani
Re: TDM-1 results reported @ ASCO annual mtg 2012 now in New England Journal of Medic

welcome--you are new to reading the literature on treatments for her2+ breast cancer. Let me help explain why we can't answer your question.

It (whether herceptin alone is enough, whether TDM1 is...
Showing results 476 to 500 of 500

 
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