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Search took 0.22 seconds; generated 79 minute(s) ago. Search: Posts Made By: Lani
Forum: her2group 09-18-2019, 09:37 AM
Replies: 0
Views: 3,486
Posted By Lani
guide to treatment deescalation: her2 heterogeneity predicts response2 preop tdm1 &

pertuzumab combo


ASCO Reading Room 09.17.2019
HER2 Heterogeneity and Response to Neoadjuvant Therapy
Study confirms lower rates of HER2 expression, pCR in HER2+ breast cancer treated with...
Forum: her2group 09-12-2019, 04:59 PM
Replies: 72
Views: 63,332
Posted By Lani
Re: Whack-a-mole next...

Vantage Logo May 08, 2019
Astra and Daiichi lay out their plan for a better Herceptin


Jacob Plieth
The companies’ DS-8201 succeeds in breast cancer patients who had failed Kadcyla, and...
Forum: her2group 09-10-2019, 09:30 PM
Replies: 3
Views: 6,018
Posted By Lani
Lasker award to Drs Slamon, Ullrich, Shepard

www.medscape.com

Lasker Awards Honor Seminal Advances in Immunology, Breast Cancer
Megan Brooks

September 10, 2019

The 2019 winners of the Lasker Awards were announced today. The awards...
Forum: her2group 09-06-2019, 10:31 AM
Replies: 72
Views: 63,332
Posted By Lani
Re: Whack-a-mole next...new target for "Lazarus effect"--keep up the hope

HEALTH NEWSSEPTEMBER 6, 2019 / 7:58 AM / UPDATED 4 HOURS AGO
Inside drugmakers' strategy to boost cancer medicines with 'Lazarus effect'
Julie Steenhuysen, Ludwig Burger
8 MIN READ
(Reuters) - In...
Forum: her2group 07-08-2019, 01:12 PM
Replies: 0
Views: 3,387
Posted By Lani
Two-in-one drug combining Herceptin with chemotherapy keeps her2+ breast cancers at

27
JUN
2019
Two-in-one drug combining Herceptin with chemotherapy keeps women’s breast cancers at bay
Like on Facebook Tweet on Twitter Share on Google Plus Share on LinkedIn
False-coloured...
Forum: her2group 07-05-2019, 09:45 AM
Replies: 0
Views: 2,566
Posted By Lani
Thumbs up determining which her2+ bc patients can forgo chemo, where dual anti-her2 treatment

suffices

Friday, July 5, 2019

PROGRESS NOTES
BCM.EDU
From The Labs
De-escalating breast cancer therapy; can some patients be spared chemotherapy?
June 25, 2019 Breast Cancer,...
Forum: her2group 07-03-2019, 06:31 PM
Replies: 2
Views: 2,641
Posted By Lani
Thumbs up First PI3K Inhibitor for Breast Cancer approved by fda

News From the Food and Drug Administration

July 2, 2019
First PI3K Inhibitor for Breast Cancer


...
Forum: her2group 06-15-2019, 08:28 PM
Replies: 0
Views: 4,116
Posted By Lani
Thumbs up “Super Trastuzumab” Extends Progression-Free Survival in Late-Line Breast Cance

AACR Publications



Cancer Discovery

News in Brief
“Super Trastuzumab” Extends PFS in Late-Line Breast Cancer
DOI: 10.1158/2159-8290.CD-NB2019-069
Forum: her2group 05-29-2019, 06:51 AM
Replies: 0
Views: 2,958
Posted By Lani
Thumbs up subcutaneouss herceptin just as effective, safe as IV herceptin

JAMAOncology | BriefReport
Subcutaneous vs Intravenous Trastuzumab for Patients
With ERBB2-Positive Early Breast Cancer
Final Analysis of the HannaH Phase 3 Randomized Clinical Trial
Christian...
Forum: her2group 05-09-2019, 01:39 PM
Replies: 1
Views: 3,743
Posted By Lani
ESMO:HER2+ Breast Cancer: Treatment De-escalation Needs to Be Personalised

ESMO PRESS OFFICE PRESS RELEASES Breast-cancer-HER2-deescalation-Pernetta-Huober
HER2 Positive Breast Cancer: Treatment De-escalation Needs to Be Personalised [ESMO Press Release]

Date: 01...
Forum: her2group 04-10-2019, 11:52 PM
Replies: 0
Views: 2,450
Posted By Lani
Thumbs up TDM-1 Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer

Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer

von Minckwitz G, Huang CS, Mano MS, et al
N Engl J Med. 2019;380:617-628.
Study Summary
This phase 3, open-label trial...
Forum: her2group 04-10-2019, 11:08 AM
Replies: 0
Views: 2,406
Posted By Lani
Thumbs up her2+ Stage IV -- having surgery (on top of systemic therapy) associated w 44% increa

sed chance of survival


Surgery is Associated With Increased Survival for Patients With HER2+ Stage 4 Breast Cancer
Patients without insurance were less likely to receive surgery, increasing...
Forum: her2group 04-02-2019, 04:19 PM
Replies: 0
Views: 2,259
Posted By Lani
Thumbs up surgery helps Stahe IV her2+ bc patients live longer

PUBLIC RELEASE: 2-APR-2019
Breast cancer study by UCR medical student could help patients live longer
Surgery is associated with increased survival for patients with HER2-positive stage 4 breast...
Forum: her2group 03-28-2019, 01:00 PM
Replies: 0
Views: 2,226
Posted By Lani
biomarker combo predicts pCR to neoadj lapatinib

trastuzumab without chemotherapy in patients with HER2+ breast cancer.

Ann Oncol. (https://www-ncbi-nlm-nih-gov.laneproxy.stanford.edu/pubmed/30903140#) 2019 Mar 23. pii: mdz076. doi:...
Forum: her2group 03-24-2019, 05:35 PM
Replies: 3
Views: 3,219
Posted By Lani
Re: FDA approves Subcutaneous Herceptin for her2+ Breast Cancer

Given subcutaneously by nurse. Average visit 5 minutes. No loading dose required. No modification of dose for body weight required. Given every 3 weeks. Not to be administered by patient themselves....
Forum: her2group 03-22-2019, 11:23 PM
Replies: 0
Views: 2,182
Posted By Lani
Thumbs up intrathecal herceptin improves pfs&os in her2+bc w leptomeningeal metastasis

Breast Cancer Res Treat. 2019 Mar 11. doi: 10.1007/s10549-019-05170-7. [Epub ahead of print]
Clinical outcomes of breast leptomeningeal disease treated with intrathecal trastuzumab, intrathecal...
Forum: her2group 03-20-2019, 12:05 AM
Replies: 3
Views: 4,087
Posted By Lani
Re: herceptin injection approved!!!!

they won't--say they do not need to & bi kidding dose needed,
Forum: her2group 03-01-2019, 05:21 AM
Replies: 3
Views: 3,219
Posted By Lani
Lightbulb FDA approves Subcutaneous Herceptin for her2+ Breast Cancer

Subcutaneous Herceptin OK'd for Breast Cancer
Study found 86% of patients preferred it to IV formulation



by Ian Ingram, Deputy Managing Editor, MedPage Today
February 28, 2019
...
Forum: her2group 02-25-2019, 10:29 AM
Replies: 0
Views: 2,077
Posted By Lani
Lightbulb PET scan biomarker may be able to ID those her2+ER-s who do not need chemo, only

herceptin & pertuzunab


De-escalation of treatment strategies aims to minimize toxicity while maintaining efficacy


Roisin Connolly, M.B.B.Ch., M.D., associate professor of oncology Credit:...
Forum: her2group 02-13-2019, 03:42 PM
Replies: 0
Views: 3,278
Posted By Lani
Lightbulb new standard of care 4 those w residual her2+bc after neoadjuv chemo including hercep

tin

'Remarkable' New Benefit in HER2+ Breast Cancer
KATHERINE and T-DM1 Change Practice
Nick Mulcahy

February 13, 2019

The treatment of HER2-positive, early stage breast cancer has taken...
Forum: her2group 01-26-2019, 11:13 AM
Replies: 16
Views: 8,175
Posted By Lani
Re: Pericarditis Query

Colchicine is effective for pericarditis --it is a drug used for centuries, but a few decades ago they judged it as a drug so old it had not passed the safe & effective standards of the times, so,...
Forum: her2group 11-14-2018, 06:40 PM
Replies: 111
Views: 57,901
Posted By Lani
Re: ZW25 clinical trial - day one

zw25 trial also available in Orange County--Hoag Family Cancer Institute Recruiting
Newport Beach, California, United States, 92663

Hope this helps!
Forum: her2group 11-13-2018, 02:23 PM
Replies: 0
Views: 4,361
Posted By Lani
Thumbs up way to prevent brain injury from radiation therapy being developed

EurekAlert! Science NewsA service of the American Association for the Advancement of Science

PUBLIC RELEASE: 13-NOV-2018
Cognitive decline -- radiation -- brain tumor prevented by temporarily...
Forum: Herceptin / Tykerb 10-27-2018, 05:17 PM
Replies: 4
Views: 16,566
Posted By Lani
Re: Herceptin and Joint Stiffness

I have read on this site that asking that the benzoyl alcohol preservative be left out of any reconstitution (dilution) of a complete vial of herceptin relieved quite a few of joint complaints and...
Forum: her2group 10-24-2018, 07:41 AM
Replies: 0
Views: 3,739
Posted By Lani
Lightbulb Study: HER2+ early brst cancers where shorter-course herceptin could be

considered

Study indicates HER2+ early breast cancers where shorter-course trastuzumab could be an option [ESMO 2018 Press Release]



Date: 19 Oct 2018
Topic: Breast cancer / Bioethics,...
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