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Search took 0.11 seconds; generated 60 minute(s) ago. Search: Posts Made By: gdpawel
Forum: General Cancer News 01-22-2013, 12:57 PM
Replies: 3
Views: 2,336
Posted By gdpawel
EGF Receptor Tyrosine Kinase Inhibitors

The EGF receptor (EGFR) tyrosine kinase inhibitors (TKIs) Iressa (gefitinib) and Tarceva (erlotinib) have been included in standard treatments for advanced NSCLC. EGFR works through two different...
Forum: General Cancer News 01-22-2013, 12:56 PM
Replies: 3
Views: 2,336
Posted By gdpawel
FDA fast tracks two new lung cancer drugs

(PM Live) - The US FDA has fast-tracked two personalised non-small cell lung cancer (NSCLC) drugs from Boehringer Ingelheim and Roche/Astellas, putting the products on track for approval in the third...
Forum: General Cancer News 01-18-2013, 10:54 PM
Replies: 7
Views: 2,294
Posted By gdpawel
Yet Another Study Agrees: Functional Profiling Provides Insight

Robert A. Nagourney, M.D.

It was during the last weeks of December that a particularly interesting article crossed my desk. The study done by a group from Toronto, Canada, is entitled Variable...
Forum: General Cancer News 01-18-2013, 10:52 PM
Replies: 7
Views: 2,294
Posted By gdpawel
Gene Mutations Alone Cannot Explain Drug-Resistant Cancer

(ChemotherapyAdvisor) - The appearance of new genetic mutations during cancer therapy has long been correlated with drug resistance, treatment failure, and ultimately, relapse. But using single-cell...
Forum: General Cancer News 01-18-2013, 10:50 PM
Replies: 7
Views: 2,294
Posted By gdpawel
Cancer cells hide by going dormant

In a major breakthrough that will change the way cancer is studied and treated in the future, Toronto scientists have discovered a key reason why many tumours may return after chemotherapy.

In a...
Forum: General Cancer News 01-18-2013, 10:48 PM
Replies: 7
Views: 2,294
Posted By gdpawel
Cancer More Diverse than Its Genetics

Stephen Baylin, M.D.
Professor of Oncology
Johns Hopkins University School of Medicine

Tumor cells can exhibit different behaviors despite being genetically indistinguishable.

One reason...
Forum: General Cancer News 01-18-2013, 10:47 PM
Replies: 7
Views: 2,294
Posted By gdpawel
Genes Are Not The Only Drivers Of Colon Cancer

Genes are not the only drivers of colon cancer. A new study suggests cellular factors play an equally important part, and these not only drive tumor growth, but also affect how well the disease...
Forum: General Cancer News 01-18-2013, 07:57 AM
Replies: 3
Views: 2,336
Posted By gdpawel
Dacomitinib Bests Erlotinib (Tarceva) in Advanced Non–Small Cell Lung Cancer

Investigators are reporting improved progression-free survival (PFS) after treatment with the investigational agent dacomitinib compared with erlotinib in patients with non–small cell lung cancer...
Forum: General Cancer News 01-16-2013, 10:13 PM
Replies: 1
Views: 1,376
Posted By gdpawel
Re: Aggressive breast cancer’s metastasis molecular switch identified

This looks like some further research into microRNAs (miRNAs) that Yale researchers have been doing to shut off genes (switches) that cause and promote lung cancer.

It is known by Laboratory...
Forum: Articles of Interest 01-12-2013, 01:24 PM
Replies: 5
Views: 5,139
Posted By gdpawel
13th International Symposium on Anti-Angiogenic Agents

Endothelial Massive Calcium Accumulation Death (MCAD): Mechanism, Target, and Predictive Biomarker for Anti-Angiogenic Therapy.

13th international symposium on anti-angiogenic therapy: recent...
Forum: Breast Cancer Newsfeed 01-06-2013, 06:30 PM
Replies: 3
Views: 1,660
Posted By gdpawel
There can be a myriad of signaling pathways

There can be a myriad of signaling pathways. The simple inhibition at one node in a cascade of signaling pathways will absolutely change the dynamic and redirect up and down stream signals that...
Forum: Articles of Interest 01-05-2013, 09:54 PM
Replies: 6
Views: 4,313
Posted By gdpawel
You thought being in a Retail Pharmacy business was only for Medical Oncologists

When a pharmacy sells the heartburn drug Zantac, each pill costs about 35 cents. But doctors dispensing it to patients in their offices have charged nearly 10 times that price, or $3.25 a pill.
...
Forum: Articles of Interest 01-05-2013, 09:52 PM
Replies: 6
Views: 4,313
Posted By gdpawel
Medical Oncologists' Perceptions of Financial Incentives in Cancer Care

Jennifer L. Malin, Jane C. Weeks, Arnold L. Potosky, Mark C. Hornbrook and Nancy L. Keating

Jennifer L. Malin, Jonsson Comprehensive Cancer Center and David Geffen School of Medicine at University...
Forum: Articles of Interest 01-05-2013, 09:51 PM
Replies: 6
Views: 4,313
Posted By gdpawel
A Call to Eliminate 'Chemotherapy Concession'

(Medscape Medical News) - A new study confirms that financial incentives exist for some US oncologists in the prescribing of chemotherapy and growth factors for treatment-related anemia.

These...
Forum: Breast Cancer Newsfeed 01-01-2013, 11:24 PM
Replies: 1
Views: 1,002
Posted By gdpawel
What of Outlier Analysis?

What of outlier analysis? What of those complicated diseases whose complexity and variability challenge even the best minds? How do they continue to bang the round peg of cancer therapy into the...
Forum: Breast Cancer Newsfeed 12-29-2012, 06:17 PM
Replies: 1
Views: 983
Posted By gdpawel
Cancer Cells Interact With Non-Cancerous Tissue

The particular sequence of DNA that an organism possesses (genotype) does not determine what bodily or behavioral form (phenotype) the organism will finally display. Among other things, environmental...
Forum: General Cancer News 12-29-2012, 05:42 PM
Replies: 3
Views: 2,072
Posted By gdpawel
Personalized Cancer Care Questions Tamoxifen CYP2D6 testing

It was hoped some day that Genomic Analyses of cancer tumors would be able to identify in advance which patients will benefit from use of cancer drugs (clinical responders). The Agency for Healthcare...
Forum: General Cancer News 12-24-2012, 12:02 AM
Replies: 1
Views: 1,024
Posted By gdpawel
Gene Switches in Cancer Development and Treatment

The "mechanisms by which these genomic regions act are not fully understood." It is known by laboratory oncologists that on-off switches and back up switches constitute the controls of cancer. When...
Forum: General Cancer News 12-23-2012, 11:57 PM
Replies: 2
Views: 1,046
Posted By gdpawel
How is gene sequencing done in drug selection?

In regards to drug selection, fluorescent In-Situ Hybridization (FISH) is used to examine gene copy number variation in the tumor. Polymerase Chain Reaction (PCR) or DNA sequencing is used to...
Forum: General Cancer News 12-23-2012, 11:55 PM
Replies: 1
Views: 968
Posted By gdpawel
Gene Switches in Cancer Development and Treatment

The "mechanisms by which these genomic regions act are not fully understood." It is known by laboratory oncologists that on-off switches and back up switches constitute the controls of cancer. When...
Forum: General Cancer News 12-23-2012, 11:49 PM
Replies: 1
Views: 1,025
Posted By gdpawel
How is gene sequencing done in drug selection?

In regards to drug selection, fluorescent In-Situ Hybridization (FISH) is used to examine gene copy number variation in the tumor. Polymerase Chain Reaction (PCR) or DNA sequencing is used to...
Forum: General Cancer News 12-23-2012, 11:41 PM
Replies: 1
Views: 1,033
Posted By gdpawel
Blood Profiling

Basically, this blood profiling uses 'negative selection' to isolate alleged circulating tumor cells (CTCs). What that means is methods to 'selectively' remove circulating normal cells, such as...
Forum: General Cancer News 12-23-2012, 11:34 PM
Replies: 2
Views: 1,306
Posted By gdpawel
Texas cancer probe draws federal scrutiny

The National Cancer Institute confirmed that federal officials are taking a closer look at a troubled $3 billion cancer-fighting effort in Texas that is under a criminal investigation over a...
Forum: General Cancer News 12-23-2012, 11:32 PM
Replies: 2
Views: 1,306
Posted By gdpawel
Anatomy of A Grant

Lynda Chin is used to getting what she wants.

Chin, a physician who is the wife of Dr. Ronald DePinho, the president of the University of Texas M.D. Anderson Cancer Center, submitted a plan on...
Forum: General Cancer News 12-21-2012, 07:06 PM
Replies: 3
Views: 1,457
Posted By gdpawel
'lizbeth I just don't know what to think...

'lizbeth

I just don't know what to think about DiaTech. A number of years ago I wrote to Gary about why they posted on their website that the DISC and MTT assays (two of a number of "cell-death"...
Showing results 251 to 275 of 500
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