Anyone experiencing heavy menstruation with large blood clots on kadcyla/tdm1?
 

Since my 2nd or 3rd kadcyla infusion at standard dose 3.6, I have been had 3 heavy menstruations with very large blood clots. I know heavy menstruation is a side effect from the drug but I'm not sure about the clots which are as big as an egg. I am worried about uterine cancer or gyneo cancers. I have not seen my gynecologist for 3 years. Although my last PET scan 4 months ago didn't reveal anything abnormal in that aspect, I understand early stage cancers are not always in the form of tumor. It can be a cell mutation.

Re: Anyone experiencing heavy menstruation with large blood clots on kadcyla/tdm1?
 

YanYan,

It could be a number of things. Fibroids, perimenopause, and the effects of Kadcyla.

Have a discussion with your medical team. I know you are worried, but you did have a Pet scan in the last few months. If heavy menstruation is a side effect, chances are more likely it is a side effect, and not cancer mets.

It has been 3 years, I have a feeling that you and your gyno are about to have a reunion for a thorough checkout. Lucky you - the pelvic ultrasound.

Since heavy periods are a know side effect you could avoid aspirin, red wine, or anything else that "thins" the blood when it is around that time of the month. Eat plenty of dark green leafy vegetables and foods that have Vitamin K. Consider supplements like chlorophyll and chlorella.

Sorry about the clots, I'm sqeamish here, yikes!

Let us know what your medical team finds.