Denosumab, for bone loss prevention
 

In the recent San Antonio Conference, a very favorable report was presented for the AI associated bone density loss. Denosumab is a twice a year injection treatment. Do any of you know whether this is available or it is still under FDA review? I am taking Fosamax and having stomach pain side effects. What are the alternate treatments? The nose sprays are hormone based treatment and they may counter the purpose of AI.

Ann,

I did not tolerate Fosamax well either. My onc wanted to get me on Zometa as soon as possible. After a bone density test indicated opsteopnia, my insurance approved it. I think there were some presentations at ASCO on Zometa.

There is an unfavorable report about bisphosphonates on Medscape Today that I saw a few minutes ago. I cannot tolerate Fosamax either as it seems to potentiate the symptoms I was having in terms of aching joints and bone pain from Arimidex. Check it out.

Petesmom