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Clusterin function new target to increase response to bc drugs
Some bc drugs, including tamoxifen, and the pre-tx chemo drug dexamethasone, provoke the transcriptional induction of clusterin, which inhibits cancer cell death. These researchers suggest including an anti-clusterin antibody with bc tx to maximize effectiveness:
http://breast-cancer-research.com/co...df/bcr1835.pdf Hopeful |
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