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-   -   Clusterin function new target to increase response to bc drugs (https://her2support.org/vbulletin/showthread.php?t=31892)

Hopeful 12-27-2007 07:36 AM

Clusterin function new target to increase response to bc drugs
 
Some bc drugs, including tamoxifen, and the pre-tx chemo drug dexamethasone, provoke the transcriptional induction of clusterin, which inhibits cancer cell death. These researchers suggest including an anti-clusterin antibody with bc tx to maximize effectiveness:

http://breast-cancer-research.com/co...df/bcr1835.pdf

Hopeful


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