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-   -   Progression; New Triple Combo Wednesday (https://her2support.org/vbulletin/showthread.php?t=31578)

Lolly 12-11-2007 10:39 PM

Progression; New Triple Combo Wednesday
 
Hi All; My onc called tonight with a new plan of attack, starting tomorrow.
I stopped Taxotere/Xeloda 3 weeks ago due to H/F and other side effects, and because the chest nodules were starting to take off again. Have been on just Herceptin for a couple of weeks and continuing to show progression. So....

I'll start Avastin/Taxol/Carbo tomorrow, no Herceptin as he feels not enough data on side effects with Avastin. I'm not unhappy with this plan, as Herceptin has been slowly losing it's effectiveness for me and a break would probably be a good thing. Can maybe go back to it later if need be.
Avastin/Taxol have shown good results together, and Taxol/Carbo have also shown good results, so the three combined should make a splash!

I'll let you know how the first day went, after the dust settles.

Oh, hubby wants to know if anyone can report on desirable side effects, like maybe nymphomania? LOL!

<3 Lolly

Joy 12-12-2007 05:11 AM

What a great attitude you have. I'm sorry you are having to switch gears, but you can outwit those dumb cells. I did taxotere/xeloda for 9 months a few years ago and the H/F thing stunk! It was so toxic. So I empathize with you.

Best wishes for the new plan of attack!

hermiracles 12-12-2007 05:20 AM

Hope the new plan goes well for you Lolly! http://her2support.org/vbulletin/images/icons/icon7.gif

Blessings
Hermiracles

jml 12-12-2007 06:18 AM

Oh Lolly!
Your resilience & spirit are amazing & admirable.
I know that this combo will create more than just a "splash"...more like a SLAM DUNK!
Take good care of you &
Keep the Faith~

Jessica

MJo 12-12-2007 06:45 AM

Let me know if the nymphmania kicks in and I will buy the drugs on the black market. I have been totally asexual lately. I wonder if it's the Arimidex drying up my estrogen. No juice. Hope this post doesn't offend.

Carolyns 12-12-2007 06:47 AM

Hi Lolly,

Okay this combo will deliver the knock out punch to those mets. Sorry that you must go through this and looking forward to the time (soon) when you get a break.

Cancer kiss my ass and GO AWAY!

Love, Hope and Peace,
Carolyn

tousled1 12-12-2007 07:47 AM

Lolly,

Sorry to hear that you have progression but happy to hear that your oncologist has a treatment plan. I'm on Herceptin/Taxol/Carboplatin and so far have had good results. I have noexperience with Avastin but I've read very promising things about it. Sheila is also on Taxol/Avastin but without the Carbo so maybe she'll have some words of wisdom for you. I'll keep you in my prayers.

Vi Schorpp 12-12-2007 08:00 AM

Lolly
 
it sounds like a good plan...I have always felt you are in great hands with both your knowledge and your team of doctors. Just a small setback for a big comeback I'm sure. You are such a gift to this board, and I wish you well.

Karen W 12-12-2007 08:04 AM

Lolly,

Sounds like a good plan... one you will do quite well on, I am sure.

Karen

Believe51 12-12-2007 08:34 AM

Lolly....
 
I was so sorry to read your post but as I read on I found some comfort with the next plan of attack and the calmness in your voice. You are always in heart and especially now when you need a little cradling. Please let me know the results of what you find for the nymphomania, I will change Ed's meds too if that is the case!! LOL! (Too bad I am the one who needs it, I am not sure if I even have ANY estrogen..ROTFL!!). I wish you well Dear Friend and I know you will be keeping us posted.>>Believe51

And MJo...you are silly and I love you so.

Julie2 12-12-2007 09:04 AM

Lolly,

I have been thinking about you these days! Hope this new combo will eradicate the cancer cells and give you a much needed break. May be you should retest your tumor pathology to see if anything changed.
Wish you all the best.

Julie

SoCalGal 12-12-2007 09:47 AM

Hi Lolly,
I'm with you on what it takes to walk the path.
xoFlori

caya 12-12-2007 10:36 AM

Lolly -

Good luck with your new combo to fight the beast. Sounds like your onc. (and you) is right on top of it.

all the best
caya

StephN 12-12-2007 10:57 AM

Cooking with gas
 
Dear Lolly -
I will be thinking about you when I go for my usual Herceptin today. I remember how long it took for me to get a three drug treatment.

Is this a WEEKLY attack?

You might try some of those hormone creams if you have the energy - tee hee. I know your hubby is a great guy and will pitch in helping so you can concentrate on this treatment.

BTW - I guess your med onc did not get the "word" from the FDA about Avastin. We will keep that our secret!

Leslie's sister 12-12-2007 11:16 AM

Prayers
 
Lolly:

Just wanted to let you know that I was thinking about you and praying that all goes well, would love to see you kick that cancer in the **#)!

Lisa

Sheila 12-12-2007 11:26 AM

Lolly
I hope you get a good response...just wanted you to know that I have taken the Avastin for 6 months with Taxol and Herceptin and no Ill side effects other than the B/P..and that seems to be a problem for everyone!!!!!! I hope your first treatment went well...but do monitor the B/P

Mary Anne in TX 12-12-2007 02:14 PM

Don't know, but will pray for your husband!
As for you, I'll just bet that new routine will knock the socks off those pesky cells!
Sending up some prayers for ya, Lolly!

Kim in CA 12-12-2007 04:47 PM

Dear Lolly,

Just adding my best wishes and saying a prayer that this new combo will make the difference for you. Where the heck is that NED anyway? You two are long overdue for a little rendezvous!!

Love,

Kim

lilyecuadorian 12-12-2007 05:05 PM

Dear Lolly all my best wishes for this new combo work for you keep fighting ...

Patb 12-12-2007 06:56 PM

Lolly
Thinking of you and wishing you the best with the new treatment and
my prayers are with you.
patb


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