New gene discovered
 

It's called IKBKE, IkappaB kinase epsilon.

I am no scientist, but from my very simplistic research, I can deduce that the HER-2/neu oncogene encodes a 185 Kd tyrosine kinase (TK) receptor and tyrosine kinase is required for activation of IkappaB kinase. (Protein tyrosine kinases are enzymes that provide a central switch mechanism in cellular signal transduction pathways. As such they are involved in many cellular processes such as cell proliferation, metabolism, survival and apoptosis. Several protein tyrosine kinases are known to be activated in cancer cells and to drive tumour growth and progression.)

And Tykerb is a tyrosine kinase inhibitor, hence the name Ty(tyrosine)-k(kinase)-erb(I guess they needed to put an ending on it).

I barely understand what I just posted, but is this all starting to fall into place?

There are some here who are probably way ahead of me on this, but just thought I would share my new research... LOL!


http://www.sciencenews.org/articles/20070616/fob2.asp