Neoadjuvant Phase II HER2 study for Stage III or IV
 

Hey, isn't this drug Tykerb?
 

It's pretty bad when you recognize these by their "numbers". So is this a study of Tykerb alone?

one drug or not....
 

Hi Chrisy. I posted this just in case someone might be interested, but I can't tell either from the description whether it would be lapatinib alone... I sort of assume it would be sequential, since the pool of candidates now would be mainly composed of those who get Herceptin, but to know for sure one would have to contact the trial coordinator mentioned.

A.A.

Yes GWblahblah is Lapatinib indeed, I wish they could stick to one name only, I cannot quite see the point of having two names for each product and a reference number..but that is another debate..

Back to vaccine, Beverly what was the argument against her2 vaccine from your consultant? and why was he concerned about the UofW ones in particular?

Yes once you enroll in one then it is hard to apply for another..U of W tries to allow you on new one they make (as combined treatment), which is good.

I know that it was a tough decision for me to chose for the above reasons, but since all vaccination prog I have heard of are at phase 1 and 2 research trial, I suppose you cannot make an informed decision, prelim data at U of W were good. E75 is also meant to be good to but you cannot stay on maintenance herceptine whilst on trial.

So basically results from trials will not be ready for years, and the next phase (phase 3) for these will not be available for at least 5 years; so sometimes you just have to jump and decide to go for it! (which as suppose is inherent to the nature of 'trials'..)

Cheers all,
Kx