the abstract for this momentous piece of research--shame on anyone who relegates this
 

to lesser read realms of this website! This will certainly speed up the discovery of new preventative measures as well as the discovery of more targeted and individualized and less toxic treatments.

: Science. 2006 Oct 13;314(5797):268-74. Epub 2006 Sep 7. Links
The consensus coding sequences of human breast and colorectal cancers.

Ludwig Center and Howard Hughes Medical Institute, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA.
The elucidation of the human genome sequence has made it possible to identify genetic alterations in cancers in unprecedented detail. To begin a systematic analysis of such alterations, we determined the sequence of well-annotated human protein-coding genes in two common tumor types. Analysis of 13,023 genes in 11 breast and 11 colorectal cancers revealed that individual tumors accumulate an average of approximately 90 mutant genes but that only a subset of these contribute to the neoplastic process. Using stringent criteria to delineate this subset, we identified 189 genes (average of 11 per tumor) that were mutated at significant frequency. The vast majority of these genes were not known to be genetically altered in tumors and are predicted to affect a wide range of cellular functions, including transcription, adhesion, and invasion. These data define the genetic landscape of two human cancer types, provide new targets for diagnostic and therapeutic intervention, and open fertile avenues for basic research in tumor biology.

Where is the link -
 

- to this research. This is only a paragraph with general information, with lots of names attached.

Thanks for tantilizing us with this tidbit.

I don't know how to do links, the info on how to find it was listed and is...
 

: Science. 2006 Oct 13;314(5797):268-74.

If you go to PubMed and put in one of the authors it will take you there.

It is not a free article, but I think copyright law prevents me from posting it in its entirety.

If I am wrong in any of this or if someone wants to teach me how to "make" a link, let me know!

Lani, to post a link
 

You click the little globe-looking icon in the reply window. It is the 4th from the left, next to the undeline icon.

This will bring up a dialog box that lets you put in the URL; it's easier if you paste it on the reply then copy it into the dialog box.

It took me forever to figure that out!

wow! here is my attempt to link to this particularly reply itself
 

http://her2support.org/vbulletin/newreply.php?do=newreply&noquote=1&p=106007#

THANKS SO MUCH CHRISY!

The link
 

Hi Lani -
Thanks for trying to post the link, but it only takes me to a reply page in this site. There is no reference to a PubMed or other site in the URL you posted.

I will try searching with one of the researcher's names.

http://www.sciencemag.org/cgi/content/abstract/1133427


But requires subscription or $10 for 24 hours access. Hope this helps.

http://www.her2support.org/vbulletin...ad.php?t=25870

or

http://www.her2support.org/gene.pdf