New prognostic figures/adjuvant Herceptin?
 

Hi all,

I haven't been a member of this list although I do read it occasionally and have posted a few times in the past ('don't remember having to register to do that before).

I figure that if there is an answer to this question, someone here will have it:

Do we know which tumor has the better prognosis, if matched for all details except HER2neu status - the HER2+ one treated adjuvantly with Herceptin and appropriate chemo/hormonals, or the HER2- one treated with the same appropriate chemo/hormonals?

I know that we do not have enough evidence to say for sure. But there must be speculation?

TIA,
Debbie

I believe that adjuvant Herceptin levels the playing field as far as disease free survival is concerned. There is not enough data yet to make a determination on overall survivability (since the Herceptin adjuvant trials began in 2000). Time will tell.


Kind regards

Becky

I have read the same as Becky.

HER2 positive breast cancer is a more agressive cancer and has a higher rate of recurrence. With the herceptin recurrence rates have been lowered.