I started Xeloda on Thurs. 2/12/04. No problems currently. Pharmacist told me it can cause a cough, told him I already had one. Also, it can interact w/blood thinners. I don't have an ulcer where radiated on left side of neck, but skin mets there are really irritating the area and it itches. I put aquaphor salve on it and take benydral to relieve itsome. Sorry it took so long to reply. Good luck to you. Velva