Switch to Fulvestrant and Palbociclib vs No Switch in Advanced Breast Cancer With Ris
 

Switch to Fulvestrant and Palbociclib vs No Switch in Advanced Breast Cancer With Rising ESR1 Mutations During Aromatase Inhibitor and Palbociclib Therapy

https://www.thelancet.com/journals/l...555-1/fulltext

Note the "take home message" section and DO's comment. But I think one of the key point is the use of liquid biopsy to change regimen.

https://www.practiceupdate.com/c/142...1&lid=20849614