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-   -   Paclitaxel With Trastuzumab and Lapatinib in HER2-Positive Early Stage Breast Cancer (https://her2support.org/vbulletin/showthread.php?t=58711)

'lizbeth 07-29-2013 10:00 AM

Paclitaxel With Trastuzumab and Lapatinib in HER2-Positive Early Stage Breast Cancer
 
http://www.clinicaltrials.gov/ct2/sh...m=her2&rank=69

Official Title: The Feasibility of Paclitaxel With Trastuzumab and Lapatinib in HER2-Positive Early Stage Breast Cancer

Sponsor:
Memorial Sloan-Kettering Cancer Center NY

The primary objective of this trial is to determine the feasibility of this regimen in patients with node-negative HER-2/neu overexpressed /amplified breast cancer with a tumor size of < 3 cm. The regimen is considered feasible if patients are able to complete the paclitaxel, trastuzumab, and lapatinib (THL) portion of the regimen without a dose delay or reduction or grade 3 or greater QTc prolongation.


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