Anybody else ER+/PR+/HER2+++ BRCA 2 +?
If you are triple positive and BCRA2 +,
Will you share your treatment protocol? I had stage 1 IDC 1.3 cm partial mastectomy of the right breast 1/14 Taxol/Herceptin 7/12 rounds I plan oopherctomy this summer and bilateral mastectomy with reconstruction in the fall. Currently NED! I want to stop the taxol, but continue Herceptin. I have started experiencing chemo brain this week. That is scary! Please share your experience and any recommendations. Thank you! Loren |
Re: Anybody else ER+/PR+/HER2+++ BRCA 2 +?
Just saw your query.. No I tested negative for BRCA.
I don't know how/if that might influence your protocol. The FORCE website might be helpful www.facingourrisk.org Warmly , Marcia |
Re: Anybody else ER+/PR+/HER2+++ BRCA 2 +?
You can see my signature and what I have done!!
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Re: Anybody else ER+/PR+/HER2+++ BRCA 2 +?
I am curious - why did you opt out of the Platinum Salt and only chose the Taxane for chemotherapy? I have always heard that Carboplatin or Cisplatin have effectiveness for the BRCA cancers.
I went on the National Cancer Institute's website and found a ton of info on the BRCA mutations. Quote:
I sacrificed significant cognitive function. I feel it reduced my quality of life for a minimum of 5 years, especially my work life. I am not going to tell you more chemo is better. It doesn't really work like that. You've already done 7 chemos and have a plan for prevention with the oophrectomy and the double mastectomy. And you will be on Herceptin for the full year. Sounds like a wise plan to me. |
Re: Anybody else ER+/PR+/HER2+++ BRCA 2 +?
My oncologist said new research indicated 12 weekly treatments of Taxol with Herceptin was just as effective (if not more) as TAXOTERE/Carbo platinum/Herceptin 6 doses every three weeks. She said it was less toxic, too.
I did one more treatment 10 days ago. I opted out of taxol last week because the peripheral neuropathy was awful! I meet with onco tomorrow. When we started the treatment plan, I did not know that I was BRCA 2+. I want to discontinue Taxol. My brain is clearing and the neuropathy is lessening. But I have fear it will be permanent if I continue. Thanks for the info. You're very resourceful. |
Re: Anybody else ER+/PR+/HER2+++ BRCA 2 +?
Hello again,
I think you are on top of the cancer and your options. Good luck with convincing the oncologist to drop the last 4 taxanes infusions. You also have quite a bit of anesthesia in your future with the upcoming surgeries. That was tough on my brain function. I know what you mean about the BRCA testing. It would be better if they tested sooner, but they usually don't. Exercise helped me quite a bit. You have the challenge of the neuropathy, but brisk walking is so healthy for us cancer survivors. Keep us posted |
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