I-SPY 2 TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Can
 

http://www.clinicaltrials.gov/ct2/sh...y+stage&rank=8

Drug: Neratinib
Drug: ABT-888
Drug: Standard Therapy
Drug: AMG 386
Drug: AMG 479 (Ganitumab) plus Metformin
Drug: MK-2206 with or without Trastuzumab
Drug: AMG 386 and Trastuzumab
Drug: T-DM1 and Pertuzumab
Drug: Pertuzumab and Trastuzumab

I-Spy is in Phase II and could be a great opportunity for someone to receive less toxic treatment and improve standard of care.