How long can herceptin/tykerb work?
 

Been on herceptin/ 1500mg daily tykerb since may...what experience does everyone have with the length of time before it stops working?

Re: How long can herceptin/tykerb work?
 

Hi,

I started Herceptin & 5 pills (1250mg) Tykerb in April 2011. For the first month I was on and off Tykerb due to severe hive. I restarted Tykerb from 2 pills in May, and then increased the dose little by little up to 5 pills until Aug. 2011. During those months my body could adjust with Tykerb without developing the hive. I've continued H&T, but have added Taxol since May 2012 due to mets in lungs, and so far this comb is effective.

Kassy's BC history
May 2010 Dx: 2.4 cm ER -/ PR - HER2 3+ Stage 3
Jun 2010 Adjuvant chemo: TCH
Sep 2010 Mastectomy, 13/21 lymph nodes involved
Oct 2010 Herceptin + Navelbine
Mar 2011 Lymph nodes biopsy surgery 3/3 cancerous
Apr 2011 Herceptin+ Tykerb
Apr 2012 mets in mediastinal lymph nodes; now stage 4 ;(
May 2012 added Taxol to Herceptin &Tykerb
Jun 2012 CT showed decrease in the size of mediastinal and right hilar lymph adenopathy
Aug 2012 CT showed no significant mediastinal or hilar adenopathy!

Re: How long can herceptin/tykerb work?
 

Response (and resistance) to Herceptin and other therapies varies from person to person. It is one of the reason why, as a group, we are lucky to have several alternative therapies to try.

Re: How long can herceptin/tykerb work?
 

So there is no average time to be on this combination before it stops working?