Diagnosed 2/2005, age 44
Lumpectomy 3/4/05
0/6 nodes
re-excision 3/17/05 for clearer margins
Stage 1, 1.7 cm, ER+ 75%, PR 4%, HER2 5.6 on FISH, grade 3
4 AC, 12 weekly Taxol w/Herceptin
Herceptin continued every 3 weeks for a year
bi-lateral masectomy 9/05, reconstruction continuing
oophrectomy at same time
Arimidex for 5 years

My info
 

Diagnosed 9/04
Stage 0
DCIS right breast, comedo type ER+
Lumpectomy
33 rads
Refused Tamoxifen

Diagnosed 9/05
Stage 1
Bilateral mastectomy (chose prophy for left breast although it was healthy)
SNL-negative in 3 nodes taken
IDC .7cm, DCIS (comedo) 3 cm
Her+++ Er+(weakly)/PR-
Completed 9 of 12 Taxol/Herceptin infusions
Will stay on Herceptin every 3 weeks through October
Will begin AI after Herceptin treatment finished
PET and brain MRI clear 12/05

Dx July 2001, age 36
15 cm tumor! (did NOT show up on mammogram?!) presented as bloody nipple discharge) 11 + lymph nodes
ER/PR-, Her2+
Stage III
Treated with mastectomy, A/C, weekly Taxol, followed by one year of Herceptin
Radiation
Prophylactic mastectomy on remaining breast
Reconstruction
Last date of herceptin--March 2003
NED!!! Celebrating 5 years of survival this summer
Made it to 40 and counting!

Found lump in shower; Went for mammogram and ultrasound and they did a biopsy on my left breast and a lymph node on the spot; Diagnosed in 11/06 at age 36; Tumor was 1.2 cm, 7 of 12 lymph nodes; Grade III; Stage IIIA; ER - /HER2 +++; Finished 4 Rounds of AC; Finish 12 weekly Taxol/Herceptin on Thursday (YEA!); Meet with Radiologist next Tuesday; and will be on Herceptin for the rest of the year.

Love, Lisa

My story
 

10 YEAR BREAST CANCER SURVIVOR
-- --------------------------------

Jan. 1996 - diag. with Infiltrating ductal carcinoma to left breast. Had
modified ratical mastetomy with immediate tram flap
reconstruction. Was on Adriamycin/Cytoxin/5FU

Jan. 1999 - Recurrence to auxilla on left side and also met. to liver.
Treated with 2 rounds of Taxol and had a stem cell replacement
with very high dose chemo. In hospital 30 days during
transplant. Found out at this time that I was Her2 possitive
and started on Herceptin in Dec. 1999

Jan/Feb 2001 - recurrence again in liver - 1 tumor.
Treated with Navelbine/Herceptin - 8 months
Gemzar/Herceptin - 8 months
Xeloda/Herceptin - 8 months
tumor never completely destroyed.

Sept. 2003 - Had Radio Frequency Abalation to liver for tumor.
Tumor returned around 8 months later

July 2004 - Decided to try resection of liver. Surgeon removed
half of my liver and along with it the tumor.
Liver has grown back nicely and so far no tumors in
the liver.

Feb. 2005 - Recurrence to lymph node behind head of pancreas
Treated with Abraxane for 8 months when rescanned
and showed another small tumor next to the first lymph
node. Was taken off of the Herceptin when started
Abraxane.

April 2006 - Just took my first treatment of TAXOL/CARBOPLATIN/HERCEPTIN

Well ladies, that's my story and I guess I'm sticking to it (and not because
I want to) haha . It's been a long road but I can say that I have been enjoying my life to the fullest and plan to continue. So as you can see, cancer does not have to be a death sentence. Keep fighting and learning as much as you can about this disease and one day hopefully there WILL be a cure.

I will be making the BREAST CANCER 3-DAY WALK HERE IN TAMPA FOR ALL OF US.

Take care

See below...
 

There ya go....

Dx Dec. 23, 2004
Stage 3 & IBC
Invasive Ductal Carcinoma
High Grade Intraductal Carcinoma
Nuclear Garde 3, rate 3, tubular 3 = 9/9 poorly differ.
Lymphatic dermal invasion
ER/PR Negative
HER2 Positive 3+
Lymph node involved (but never done surgery)
Start Chemo ECT does dense 6 cycles (every 2 weeks)
12 days after last chemo, Left mastectomy
Path report after mastectomy:
No tumor after chemo
but still extensive involvement by residual intralymphatic high grade ductal carcinoma and involvement of dermal lymphatics
no evidence of residual invasive or in situ ductal carcinoma
maegins free of malignancy
45 days after 26 rads & started Herceptin every 3 weeks, will finish in June 2006
Jan 2006 UW Vaccine, the 3rd and last one in March 2006
Last Pet,Bone, CT, Mam, Ultrasound shows NED
It's a tough one but my oncologist thinks I can make it because I'm tougher.

Diagnosed 1998 at 45 years old with IDC 8mm tumor right breast,ER+ HER2- 11 nodes dissected none positive. Had lumpectomy with rads. No chemo, 5 years of Toremifene. No hx of bc in my family.

Diagnosed March 2005 with IDC with DCIS right breast 7mm, ER+, HER+++ (IHC test) no nodal involvement. Had mastectomy, was put on Tamoxifen, no chemo. Opted for ooph in October 2005 to be put into menopause and to begin Arimidex.
Annual mammogram in March on remaining breast showed NED.

Petesmom

Hi All,
Diagonosed in Feb 2004 at age 49 after routine mammogram showed calcifications. No family history.
tumor .4 cm
nodes negative
er + pr indeterminate
her2neu+++
Lumpectomy April 1, 2004
4 rounds Adriamycin and Cytoxan because Oncotype Dx test showed a high probablility of recurrence.
Radiation
Started one year of herceptin in Nov. of 2005. Yes, that is late but it seems like a good idea.
I also had ovaries out due to cysts on both of them in 2004.
Femara.
So far the femara and herceptin have been ok. Now I just need to lose the weight I gained while on the chemo. Eat smarter and exercise more.

Hi, Lump found during mamogram November 2003 Age 44, 1.3 cm I had a lumpectomy no nodes stage 1 I had 4 a/c and 37 rads.and now tamoxifen . er/pr+ Her2+++ no herceptin to far out from chemo my onc. didn't think I should take it.Love and peace to you all.
thanks Leslie

dx: Nov '03 @ 43 years old
invasive ductal carcinoma w/ paget's disease of the nipple
Rt side mastectomy w/ reconstruction (simple implant)
10 nodes removed, 1 positive
stage 2B
Her2neu +
ER/PR +
6 treatments TAC, finished May '04
Tamoxifen for a year, then switched to Arimadex

Very early recurrance discovered Aug '05
7 mm spot on muscle under implant
Rice sized tumor in node under right arm
5 microscopic spots in chest nodes
3 microscopic spots in lungs
Aug '05 - discontinued Arimadex
Sept '05-Jan '06 Carbo/Taxol/Herceptin
Dec '05 - added Aromasin
Feb '06 - all scans clear
Mar '06 - tumor markers continued to drop on Herceptin only
Apr '06 - tumor markers at 12, staying steady

Currently on Herceptin every 3 weeks + Aromasin
No apparent Herceptin side effects
June '06 - next Muga and CT

Knew nothing about HER-2 until i heard a lecture!!
 

Dx Sept 2003 at age 40. "lump"was lymph node with BC on it but no sign of tumor by mammo or ultrasound. Finally found primary after extensive ultrasound, bit of guesswork and several core biopsies.
ER+PR+ HER-2+++. 3/12 nodes involved. 23mm tumor. stage 2B
Sept 2003- partial mastectomy and aux clearance
Oct 2003- re excision but margins not clear
Nov 2003- mastectomy with expander inserted.
Dec 2003- May 2004 FEC x 8. (only one i know who had that many!!)
Aug 2004- expander changed over to silicone
Oct 2004- ovaries out
Took Tamoxifen and then changed to Arimidex last year. Oh my aching bones!
Nov 2005- started late Herceptin through HERA trial.

I think that is all!

Here are my deets,
Jen

Dx 5-16-05, lumpectomy 5-24 at age 47
Stage I (1.1) Grade 3
Node Negative (3 removed)
ER/PR +
HER2 +
Finished 4 rounds of AC DD on 9-7-05
Finished 33 rads 11-28-05
Started 1 year of Herceptin 11-30-05
Started 5 years of Faslodex 11-30-05

I found my lump when it caught on my bra 3/5/05 at age 66.
Mammogram and ultrasoound 3/8/05. Needle biopsy 3/9/05. Told of results 3/10/05: HER2/NEU+++, ER+++, PR+.
Lumpectomy & sentinel node biopsy 4/13/05: IDC 1.5cm high grade tumor, DCIS. Sentinel node negative. Stage 1.
Reexcision for wider margins and to implant port 4/25/05.
A/C x 4 starting 5/2/05 ending 7/5/05.
Hospitalized 6/24/05 for 3 days because of zilch neutrophils and low hemoglobin & hematocrit.
Started Herceptin 7/19/05 every 3 weeks for 1 year.
Rads x 30 ending 9/29/05.
Started Arimidex 10/11/05.
Mammogram 11/9/05 NED!!!
Muga scans every 3 months until onc decided LVEF was improving not going down. I thank exercise & COEnzyme Q10 for that.
I am walking in the Race For The Cure on May 13 with my daughter, daughter-in-law and 4 grandchildren. 3 more and we could have been a team!!
Love this site!
Marlys

dx 3/17/03 - age 40

IIIC/ER/PR-/Her2 +++/Grade 3
neo-adjuvant T(taxotere)E(epiruicin)C x4
lump/SNB
TEC x2
radiation, 3mo herceptin/navelbine
reoccurrance - had complete axilla dissection
herceptin/taxotere
reoccurrence - entered xeloda/lapatinib clinical trial 6/05 (xeloda arm only)
4/06 trial stopped due to positive results - we all now get lapatinib(tykerb)
will get re-scanned in june '06...
Shell

diagnosed 10/04

.6cm IDC with other areas of DCIS with comedo necrosis Stage 1 Grade 3 7/9 er+/pr+/Her2+++ 0/14 nodes

2 lumpys to get clean margins

Dose dense A/C X 4 - finished 2/05

33 rads - finished 6/05

Arimidex for 5 yrs

March 06 CT scan -- NED

routine mammogram April 28, 2005
call back for suspicious 'spot'
May 18, 2005 repeat mammo and ultrasound-8mm 'spot'...told, "don't worry, it does not look like cancer"
May 23-biopsy
May 27-results...left breast-7mm tumor, invasive lobular carcinoma with LCIS...no clear margin. ER+, PR+, Her2 +
June 7, 2005 MRI..nothing unusual
June 14, 2005 bilateral mastectomy...sentinel nodes..2 on left, 1 on right...negative No other cancer found...
Diagnosis Stage 1 Grade 1
July 1, 2005 CT scan...spot on liver, bone scan-all clear
July 7, 2005 MUGA (65%), liver scan-hemangioma (nothing to worry about), oncotype DX (high intermediate risk of recurrence...)
Aug. 10, 2006 chemo...A/C first of 6
Sept. 7, 2006 to ER with high fever and infection...month break from chemo to recover
Only had 4 A/C treatments due to severe side effects
Oct. 20, 2005 MUGA (65%)
Oct. 26, 2005 first Herceptin...every 3 weeks for a year
Jan. 24, 2006 MUGA (65%)
CA 25/28 <3.5
next MUGA May 4, 2006

ps!! Arimidex for 5 years!!

DX march'06, 1.4 IDC, grade 3, Nottingham 8, 2 sent. lymph negative,

ER/PR neg, HER2 3+. Second wide excision attained clear margins.

Starting Herceptin (every three weeks for one year).

Radiation begins next week.

Med. Onc gave me the choice of chemo, chemo+Herceptin or Herceptin alone.
I chose the latter. WILL HERCEPTIN ALONE DO THE TRICK???? How can they test to know whether it is working?

Great Idea! Thanks Rhonda
 

Was dx. 4/15/05 (age 54)
3MM tumor
node neg. er postive, pr negative
her2 +++ postive by FISH
grade 1
Lumpectomy followed with 32 treatments of radiation
Recently had Oncotype DX test performed came back off the charts. 4/19/06
Went for PET scans , CT scans and bone scans on 4/26/06
After scans results come back I will begin chemo/and herceptin.
I am one year out from dx. and I have finally found an answer.
All the dr. went by the tumor size and the node negative status and
did NOT think the Her2 postive required chemo or herceptin.
THEY ARE WRONG....went to L.A. and saw Dr. Slamon.....

Jean

Tag on
 

I am on Arimidex since 5/05....

Jean

Jean,

What made you push for the Oncotype DX? I am simply amazed that such a small tumor came back off the charts. I am glad you pushed and that you are able to start chemo and herceptin.

Best of luck to you.

Karen

Mimima
Whether or not to have chemo is your call. At least your doctor offered options. With about the same diagnosis as you but with slightly small tumor, 9mm and grade 2 rather than three, the standard of care when I was diagnosed was AC chemo, November 2004. They wouldn't give me Herceptin as I was node negative. I refused that chemo. Finally 9 months after diagnois (I did 35 rounds of radiation) I was offered Herceptin with or without Taxotere. I chose to go with the chemo/herceptin combo as the studies had shown the chemo helps the Herceptin work. However, I don't think there are any studies for taking it as I have, several months after diagnosis--I am still on it, with 3 more months to go to complete the year.
I have no advice to you other than I chose the chemo with a less aggressive, smaller tumor. And I don't think they really can tell if the Herceptin is working. I would have the Bayer Serum test done before Herceptin and there maybe another test someone else can suggest.
There are a lot of people here that can answer most any questions you have.
Radiation treatment shouldn't be too hard on you, particularly since you are having it before any chemo.
Wishing you the best--
Janet

Thanks, Janet. I'll let you know about my followup Second Opinion (Monday).

This is my first participation in a "Forum" and I may not know about threads and how to answer, but I'll learn. I also am quickly looking up "ned", "MUGA", etc.

I have always loved learning but, frankly, I'd rather be studying Italian.

I picked the Herceptin alone (I thought "we got it") and I was lymph neg.
It was the HER2 +++ that alarmed me. Mimima

My Stats
 

DX on April 29th, 2005
IDC
ER/PR/Her2neu+++
StageIIB
May 19th 2005 2nd operation to clean margins and SNB
No nodes involved
4 a/c q 3 finished August 10th
12 weekly Taxol and Herceptin Finished November 16th
Every 3 weeks herceptin to end on August 16th of 2006.

Age at dx, 41

Now: Happy healthy and very grateful for all the BC boards and support!

RAndi

10-03-05 Diagnosed after clustered microcalcifications found on routine mammogram at age 51 post menopausal.
No lump to feel; although surgeon said he could feel firmness in the area.
10-12-05 Biopsy 6mm / HER2+++ (IHC test) / spotty margin.
10-19-05 Lumpectomy 4mm more for total of 1cm / margin clear / sentinol node negative/ Her2++(IHC test) / ER+ PR weakly+ / Grade 3 / Stage 1 IDC
November 2005 began Adriamyacin & Cytoxin Every 3 wks x4
2/10/06 began Taxol w/Herceptin every wk x12
Will continue with Herceptin every 3 wks until Feb 2007
7/7/06 Had last of 30 rads
7/11/06 Beginning to take Arimidex for 5 yrs.
4/25/06 Mammogram of affected breast; couple of benign calcifications;negative for cancer.
Sept 06 Onc will order full mammogram & MRI of rt breast due to high density.
Prognosis:Onc would be "shocked if there was a recurrence. Should live a long & happy life." I'm keeping my fingers crossed & praying every day.

Diagnosed October 2002

Large tumour(6-8cm) right breast.3-5 nodes. Pre op chemo - doxorubicin/doxetaxol(6 rounds)
Feb 2003 Mastectomy followed by 6 weeks rad.
May 2003 Hera trial - 4 months into it skin mets- tiny.Off trial and receive Herceptin anyway and taxol.
4 months taxol - skin recurrence.On to navelbine - can't remember how long - skin recurrence.
Xeloda - went well for a long time and then stopped it just before op for other side Feb 2004 2cm tumour ( new primary)and 5 nodes.
Can't remember - shortly after skin mets and carboplatin - 4 months - no response.
2005 Tried Xeloda again - but no response this time.
Late 2005 - Doxil - 4 rounds - just stable.
All of these chemos with herceptin - now having a break after several difficuklties with port ops. Will have radiation ( 3 weeks) soon just to try something different and have a break.

Lindaw

Rhonda you always have a good idea!
 

I haven't posted for awhile, and here is Rhonda with another good way for us to get to know each other;

2001 Stage 0 Radation and tamoxifen Age 44 (and mama of 4)


2004 Stage 4 Her 2 +++ er/pr -, metastasis to all 4 lobes of lungs, Navelbine, Herceptin and Seattle clinical vaccine trial. Prognosis of 21 months

2006 CAT scan this week continues to show no evidence of disease..now on Herceptin alone every 3 weeks, and feeling fine!

Love, Kim From CT

Was Dx July 2000 Stage 111B 3 out 10 nodes positive

had 4 rounds of chemo, then a lumbectomy without clear margins, so then had a

Mastectomy with reconstruction, and 2 more rounds of chemo
then 27 radiations
14 months off then a reocurrance of a lymp node
6months of navelbine and herceptin and another 20 something radiation treatments
4 months off and cancer then moved to lungs and bones. 20 something more rads to spine.
Had more navelbine, then taxotere and carbo, then xeloda, then back to navebine, then gemzar, then xeloda again.
Last- 33 novalis radiation treatments to lung.
Finished radiation Dec 2005 and am stable at the moment. Patty H

Diagnosed 2/22/05, Double Mastectomy 4/5/05, Age 42

Stage I-Less than 1cm (second site found 2mm same side)
No node involvement
ER/PR-
HER+++
4 rounds of AC dose dense
4 rounds of Taxotere w/Herceptin
Currently on Herceptin every 3 wks until mid Sept 06

Went aggressive on treatment despite docs recommendations since sister diagnosed at age 31, passed at age 41 from BC.

Diagnosed 7/01

42 yrs.
Found lump while breastfeeding
ER-/PR-, Her2+ (Fish)
2 cm. & additional invasive areas
1 pos. node
Left MRM
No radiation
NSABP clinical trial: randomized to herceptin arm. A/C x 4, taxol & herceptin x 4, herceptin x 48
Currently NED.
Forever grateful for the opportunity to get herceptin.

Name is Sheryl.

Dx 11/19/05 (age 50+), Modifed radical 12/05/05
Stage 4, mets to T12 and liver
Node positive (all nodes removed)
ER/PR-
HER2positive (FISH 7.5)
Finished 3 rounds of ATZC (Adria,Taxotere,Zometa,Cytoxan) on 2/23/06
Will begin Herceptin/Taxotere/Zometa on 5/03/06 (will be done July 06) 3 weeks on, 1 or 2 weeks off
Met on liver has shrunk 50% (<1" in size now) - Met on T12 spine is stable. Recent bone scan show no new mets...yippee!

Still on the planet! Blessings from Minnesota!

Sherry
Stage IV Lumpectomy Sept 25, 2002
Dx. Sept 11, 2002 confirmede Friday 13th 2002
Her + ER neg.
Many chemos
Unable to finish any schedule of chemo due to low cts and neuropathy caused by chemo.
Herceptin first weekly, now q weeks since first chemo Oct 4, 2002Last month had cerebral bleed, renal failure and chf. Doc called family in,.
Comma 4 days. Pulled out of it, by Grace of God and many prayers.
Plt ct 40000, no longer able to produce plts.
have decided no more chemo.

NED;dx2001,T1c,CAFx6+IMRT+tamo,arimidex,eom
 

That's all folks....

Dx Jan 2005 (age 48)

Lumpectomy 14th Jan Left Breast
(Tumor 3+cm IDC Grade 3, +DCIS 1/15 nodes)
Mastectomy 28th Jan Left Breast
ER/PR- HER2+++
A/C x 4 Taxol x 4
Entered phase one trial for potential vaccine for the HER2 protein.

Finally commencing Herceptin next Tuesday (nearly 9 months post chemo) paid for partly by workmates, health society and family. I'm soooo HAPPY.....

Best wishes to all

Helenhttp://www.her2support.org/vbulletin...cons/icon7.gif

My dx
 

Dx September 1998 Stage 1 BC ER+ 35 years old.
Had masectomy October 2,1998

Then December 1998 I started treatment 4 rounds of Adrimicyn and Cytoxin finished in Feb 1999 after that was on Tamoxofin till August 2001. When I was dx with stage IV BC Mets to my liver many tumors and leisions was told to many to count. That's when my world fell apart. Started weekly Taxol treatments and was put on arimidex. Oncologist sent for my tumor and had it retested were I was diagnosed as being strongly her2pos. He add herceptian to the taxol and I responded to it great. June 2002 I was taken off the taxol and just kept on herceptin every 3 weeks. Till my stubborn mets in the liver decide to wake up in January 2005. Then I was put on Navebine and herceptin till may 2005 didn't work to good for me so the doctor started me on carbo/taxol/herceptin till I built up antibodies to the carbo and was taken off that and just stayed on the taxol/herceptin.3 weeks on 1 off. As of May 3,2006. My recent Ct scan shows progression again http://www.her2support.org/vbulletin...lies/frown.gif So I think its time for a new set of cocktails as I call them. We are going to go with Gemzar till the Lapatinib is FDA Approved then he will put me on the Xeloda/Lapatinib. Oh and I was getting monthly Zoledex shots too. Stopping that now too he is leaning on giving me the Faslodex now. I am truely amazed by everyone in this support group the strength and courage gives me so much hope for the future. There is one thing my oncologist told me when I asked him about my her2 status he looked at the surgical path report and it said her2pos 4+++. Is there such a thing? I am hopeing it was a typo lol. Well thats my story and I sticking to it lol. On with another battle to knock these peskly liver mets out. And I have been very lucky thus far that my liver function through this whole ordeal has remained normal http://www.her2support.org/vbulletin...lies/smile.gif . I pray for everyone here you all are truley my hero's..........

Love and Hope Always

DX September 6 2005 (39) Invasive Ductal Carcinoma
Right Mastectomy tram flap reconstruction September 26 2005
Stage II Grade III Nodes 0/5, ER+/PR- Her2+ 3.0 amplified
4 cycles AC
4 cycles Taxotere
Started Herceptin March 28 2006
Started Tamoxifen April 12 2006

Diagnosed November 2003, Age 45, Invasive Ductal Carcinoma
Left breast lumpectomy - Stage II, Grade III, Nodes 2/6 , Her2 +, ER+/PR+
Not clear margins, went back into surgery and had clear margins
Right breast mastectomy - in situ cancer found
Had pet scan; found tumor in my lung; looked like it was mets; operated - benign tumor; moral - don't jump to conclusions based on Pet scan.
4 cycles AC starting April 1, 2004
12 weeks taxol with herceptin
40 weeks more of taxol only
Radiation to left breast
Tried tamoxifen, too many problems. Currently only taking celebrex.

Best,
Monica