Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

Lorraine got into the original t dm-1 eap in 2010, w/ an extensive hx pf pre-treatment w/ all kinds of drugs, incl. a lot of adria , an anthracycline . in fact, she was txed w./ adria alone the last few weeks to get her into the eap, to keep her liver counts w/in eap limits. part of the argument to get her in was that since she was close to life-time limits on anthracyclines she would have to stop them soon anyway, then what ??
eap criteria in 2010 primarly focused on having progressed on her2 therapy, taxanes and tykerb. so i think some exposure to anthracyclines is very common in many t dm-1 candidates at this point

Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

Three additional sites posted today.

Go to end of this thread under Clinical Trials:

http://her2support.org/vbulletin/sho...236#post284236

Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

FDA will make its decision on whether or not approving the drug by Feb 26,2013, does it mean if the drug does not get approved the trial will be closed? I hope they will approve it !!!

Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

Can't imagine the FDA kicking back the T-DM1 application again!

THREE new T-PAS sites open for people to get the drug closer to home (making the total I have at 16 sites):

Two more sites just came in from Genentech:

15. Dr. Kenyon (Samaritan Oncology, OR)
Dr. Peter Kenyon
3640 Northwest Samaritan Drive Suite 161, Corvallis, OR 97330
Phone (541) 768-4950


16. Dr. Wolff (Johns Hopkins, MD)
Antonio C. Wolff, M.D., F.A.C.P.

410-955-8964
Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
Baltimore, MD

Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

Just got word of two more T-PAS sites for T-DM1 treatment opening.

17. Donald B Wender, PhD, MD
Siouxland Hematology Oncology
230 Nebraska St
Sioux City, IA 51101
(712) 252-0088
https://www.navigatingcancer.com/clinics/siouxland


18. Julie A. Means-Powell, M.D.
Vanderbilt-Ingram Cancer Center
691 Preston Building
Nashville, TN 37232
615-936-8422
http://www.vicc.org/

Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

The work continues! Two more sites just opened - here it is the first week of January.

19. Denise Yardley, MD
Sara Cannon Research Institute
250 25th N Ave Suite 110
Nashville, TN 37203
877-MY-1-SCRI (877-691-7274)
http://sarahcannonresearch.com/


20. Ian Krop, MD
Dana Farber Cancer Institute
44 Binney Street
Boston, MA 02115
(617) 632-3000
http://www.dana-farber.org/

Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

New T-PAS site just opening:

21.
Dr. Steven A Limentani
Carolinas Hematology-Oncology
Address: 1100 South Tryon Street, Charlotte, NC 28203

Phone (704) 446-9046

Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

Redwolf -
Your doctor would have to check and see if you have had too much in the anthrocycline category. Hope not!

Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

These sites for T-DM1 T-PAS continue to open at a good clip! Some of these were also early trial sites for this drug.


22. Jenny C. Chang, M.D.

The Methodist Hospital Research Institute
Director, Methodist Cancer Center
The Methodist Hospital
6565 Fannin Street
Houston, TX 77030
713-790-2700

Clinic Phone: 713-441-9948
Research Phone: 713-441-0629
Email: ccresearch@tmhs.org


23. Dr. Taral Patel
Mid Ohio Oncology
3100 Plaza Properties Blvd
Columbus, OH 43219
(614) 383-6000

Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

Additional site to report:


24. Joanne Blum, M.D., ph.D., F.A.C.P.
Texas Oncology

Address: 3535 Worth St, Dallas, TX 75246
Phone (214) 370-1000

Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

New T-PAS site just opened. T-DM1 has been given here, but now it has this designation.

25. Julie Gralow, MD
Seattle Cancer Care Alliance
825 Eastlake Ave E,
Seattle, WA 98109
(855) 557-0555
http://www.seattlecca.org/about-us.cfm

Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

Two more sites to announce. Maybe the last before the T-DM1 gets FDA approvel???

26. Dr. Kathy Albain
2160 S 1st Ave # 109
Maywood, IL 60153
Phone:(708) 216-9000





27. Dr. StanleyWaintraub
John Theurer Cancer Center
92 2nd Street
Hackensack, NJ 07601
Phone: 551-996-5864

Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

Does anyone know the status for T-DM1 FDA approval for Esophagus cancer treatment? There has been alot of good results in clinical trials.

Re: Check the ANNOUNCEMENT on t-dm1 - Plus EAP sites UPDATES
 

http://www.cancer.gov/clinicaltrials...rchid=11850678

http://clinicaltrials.gov/show/NCT01641939

I see a phase III trial for advanced gastric her2 positive cancer. The first received date was July 2012, so I would guess it is too soon for approval.