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Breast Cancer Meeting Highlights

Breast Cancer Meeting Highlights News fro recent ASCO and San Antonio Meetings

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Rating Thread / Thread Starter	Last Post	Replies	Views
Tykerb + Fulvestrant not useful in Her2+ ER+ metastatic pts. tx w/AI Hopeful	12-13-2010 10:37 AM by Hopeful	0	1,083
Lab Findings: Tykerb + Insulin/Insulin-like growth factor receptor for ER resistance Hopeful	12-13-2010 10:19 AM by Hopeful	0	1,123
Lab Findings: T-DM1 + PK13 inhibitor shows promise for Her2+ bc Hopeful	12-13-2010 10:14 AM by Hopeful	0	1,336
Discordance in Hormone Receptor and HER2 Status in BC during Tumor Progression Hopeful	12-13-2010 10:11 AM by Hopeful	0	1,157
Herceptin + Pertuzumab active in Her2+ bc w/o chemo - NeoSphere study Hopeful	12-13-2010 10:07 AM by Hopeful	0	1,146
Online Conference San Antonio Breast Cancer Symposium ElaineM	12-12-2010 10:57 AM by ElaineM	0	1,591
No anti-tumor effects seen in adding Zolendraic acid to chemo Hopeful	12-11-2010 08:24 PM by Rich66	1	1,346
Colon cancer risk Jackie07	12-10-2010 08:21 PM by WolverineFan	2	2,028
Her2+ Correlates to Coexisting Invasion in DCIS Hopeful	12-10-2010 09:58 AM by Hopeful	0	972
Multi-Modality tx improves brain met survival Hopeful	12-10-2010 09:56 AM by Hopeful	0	966
Brain Met outcomes for Her2+ patients enrolled in LEAP Hopeful	12-10-2010 09:53 AM by Hopeful	0	1,082
Her2+ patients Retain an Immunological Proficiency Compromised in Her2- cases Hopeful	12-10-2010 09:44 AM by Hopeful	0	1,044
TN and Her2 bc more chemo sensitive but have higher rate of brain mets Hopeful	12-10-2010 09:41 AM by Hopeful	0	1,035
Phase II trial of 4 drug combination for early Her2+ bc Hopeful	12-10-2010 09:38 AM by Hopeful	0	1,023
Neoadjuvant trial of Concurrent Trastuzumab and Paclitaxel without Anthracycline Hopeful	12-10-2010 09:34 AM by Hopeful	0	840
Response to neoadjuvant chemo + Herceptin predicts survival Hopeful	12-10-2010 09:31 AM by Hopeful	0	1,082
Retesting Her2 status in metastatic patients cost effective and relevant Hopeful	12-10-2010 09:22 AM by Hopeful	0	955
Short-term exposure to pregnancy level ER delays Her2+ tumor development Hopeful	12-10-2010 09:18 AM by Hopeful	0	955
Short-term exposure to pregnancy ER levels alters bc pathway development Hopeful	12-10-2010 09:13 AM by Hopeful	0	792
Safety of High Dose Vitamin D in pre-meno women Hopeful	12-10-2010 09:11 AM by Hopeful	0	784
Chinese Herb Fructus Cornii prevents ER+ BC in the lab Hopeful	12-10-2010 09:08 AM by Hopeful	0	869
Protective Effect of Dietary Intervention limited to high baseline Testosterone Hopeful	12-10-2010 09:01 AM by Hopeful	0	808
Omega-3 Fatty Acids for Chemoprevention Hopeful	12-10-2010 08:56 AM by Hopeful	0	814
Molecular Biomarkers for Resistance to Trastuzumab Hopeful	12-10-2010 08:36 AM by Hopeful	0	729
BC Stem Cells survive Herceptin by downregulation of Her2 Hopeful	12-10-2010 08:34 AM by Hopeful	0	827
Toxicity of Adjuvant Endocrine Therapy in Postmenopausal Breast Cancer Patients Hopeful	12-10-2010 08:28 AM by Hopeful	0	911
High baseline inflammatory signature results in lower response to AI's Hopeful	12-10-2010 08:24 AM by Hopeful	0	752
Impact of BMI on endocrine tx in postmeno HR+ BC Hopeful	12-10-2010 08:21 AM by Hopeful	0	830
Obesity at Dx associated with worse outcomes in HR+ BC Hopeful	12-10-2010 08:19 AM by Hopeful	0	773
CYP2D6 metabolism unrelated to Tamoxifen benefit Hopeful	12-10-2010 08:17 AM by Hopeful	0	799
FIRST study: Arimdex vs. Fulvestrant for Advanced BC Hopeful	12-10-2010 08:14 AM by Hopeful	0	824
At the Breast Cancer Symposium 2009 gdpawel	11-20-2010 08:52 PM by gdpawel	8	2,407
The prognostic and predictive impact of BMI on clinical outcome of HER2-positive bc Hopeful	11-06-2010 02:43 AM by Jackie07	5	1,909
Subcutaneous testosterone-anastrozole implant therapy in breast cancer survivors Hopeful	10-01-2010 06:01 PM by Laurel	1	1,262
The role of autophagy inhibition as a neoadjuvant therapy for DCIS Hopeful	10-01-2010 12:00 PM by Hopeful	0	1,067
Adjuvant trastuzumab therapy in tumors smaller than 1 cm Hopeful	10-01-2010 11:58 AM by Hopeful	0	1,199
Is it safe to use transtuzumab for the treatment of breast cancer during pregnancy? Hopeful	10-01-2010 11:57 AM by Hopeful	0	958
Evaluation of trastuzumab without chemotherapy as a postoperative adjuvant therapy Hopeful	10-01-2010 11:54 AM by Hopeful	0	954
A phase I study to assess the safety, tolerability, and PK of ARRY-380, an oral HER2 Hopeful	10-01-2010 11:53 AM by Hopeful	0	1,059
Estrogen receptor positivity in normal breast epithelium from women with breast cance Hopeful	10-01-2010 11:46 AM by Hopeful	0	782
Correlation between diabetes and ER/HER2 status in African Americans Hopeful	10-01-2010 11:40 AM by Hopeful	0	906
Survival after supraclavicular recurrence of breast cancer Hopeful	10-01-2010 11:10 AM by Hopeful	0	1,112
Can whole-brain irradiation (WBRT) be replaced by radiosurgery? Hopeful	10-01-2010 11:08 AM by Hopeful	0	925
Breast cancer at the extremes of age: Predicting recurrence and mortality Hopeful	10-01-2010 09:57 AM by Hopeful	0	1,076
Long-term outcome of node-negative early breast cancer patients Hopeful	10-01-2010 09:55 AM by Hopeful	0	893
Molecular predictive factors of response to taxanes (T) and anthracyclines (A) in bc Hopeful	10-01-2010 09:53 AM by Hopeful	0	953
Is microcalcification on mammography relrelated to bone metastasis & bad prognosis? Hopeful	10-01-2010 09:50 AM by Hopeful	0	933
In situ carcinoma (ISC) accompanying small (≤ 1 cm) invasive breast carcinoma (IBC) Hopeful	10-01-2010 09:47 AM by Hopeful	0	885
Genomic profile of screen- and symptom-detected breast cancers and association w/ DFS Hopeful	10-01-2010 09:45 AM by Hopeful	0	863
Association of phosphorylated-HER2 with relapse in patients Hopeful	10-01-2010 09:38 AM by Hopeful	0	933
Is age an independent predictor of survival and time to recurrence in breast cancer? Hopeful	10-01-2010 09:34 AM by Hopeful	0	967
Survival benefit of neck dissection for patients w/bc w/supraclavicurlar LN mets Hopeful	09-28-2010 09:57 PM by Jackie07	2	1,325
Paradoxical actions of a c-Src inhibitor on long-term ER deprived cells Hopeful	06-25-2010 11:46 PM by Lani	1	1,654
Circulating tumor cells (CTCs) and association with survival in molecular subtypes Hopeful	06-25-2010 07:22 AM by gdpawel	1	1,383
A couple ASCO 2010 related links Rich66	06-12-2010 02:42 PM by schoonder	3	1,747
Method of detection of DCIS to predict HER2 overexpression Hopeful	06-08-2010 02:07 PM by Hopeful	0	1,344
Impact of BMI on clinical outcome of HER2-positive breast cancer Hopeful	06-08-2010 07:56 AM by Hopeful	0	1,113
Early detection of recurrent breast cancer using metabolite profiling Hopeful	06-08-2010 07:42 AM by Hopeful	0	903
Biomarker changes associated with the development of resistance to AIs Hopeful	06-08-2010 07:40 AM by Hopeful	0	869
Discordance in hormone receptor status in breast cancer during tumor progression Hopeful	06-08-2010 07:27 AM by Hopeful	0	884
Should liver metastases of breast cancer be biopsied to improve treatment choice? Hopeful	06-08-2010 07:26 AM by Hopeful	0	1,016
Good news for triple positive (ER+/PR+/Her2+) bc Hopeful	06-04-2010 05:50 PM by Laurel	1	2,766
False-negative HER2 tests with appropriate positive controls Hopeful	06-04-2010 09:29 AM by Hopeful	0	1,028
Tykerb treatment for DCIS - study Hopeful	06-04-2010 09:27 AM by Hopeful	0	983
HER2+ gene expression signature specific for trastuzumab resistance and poor prognosi Hopeful	06-04-2010 09:02 AM by Hopeful	0	998
Cause-specific and all-cause mortality of HER2-positive, node-negative, T1a & T1b bc Hopeful	06-04-2010 08:37 AM by Hopeful	0	1,031
For T1a,b,N0M0 Her2+ patients not treated with chemo or Herceptin, age at dx importan Hopeful	06-04-2010 08:35 AM by Hopeful	0	953
Association of gene copy number alterations with prognostic subtypes Hopeful	06-04-2010 08:26 AM by Hopeful	0	910
Gene signature of metformin actions on primary breast cancer Hopeful	06-04-2010 08:22 AM by Hopeful	0	994
Dose-dependent interaction between tamoxifen and antidepressants on patient complianc Hopeful	06-04-2010 08:20 AM by Hopeful	0	1,042
Beta-blockers and ACE inhibitors in the prevention of trastuzumab-related cardiotoxic Hopeful	06-04-2010 08:17 AM by Hopeful	0	1,079
CK-19 mRNA-positive CTCs and Herceptin treatment Hopeful	06-04-2010 08:12 AM by Hopeful	0	1,011
Ovarian suppression + endocrine therapy + zoledronic acid in premeno bc patients Hopeful	06-04-2010 08:09 AM by Hopeful	0	1,056
ASCO: Leptin & High BMI May Reduce Her2+ Survival 1rarebird	06-03-2010 05:49 PM by 1rarebird	2	1,700
What ASCO Can Tell You About Biotechs Rich66	05-28-2010 11:59 PM by Rich66	0	2,042

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