Study links methylglyoxal stress to immunotherapy resistance in triple-negative cance

[News]

The metabolism of cancer cells may play a key role in their ability to evade the immune system. This is demonstrated by a new study conducted by researchers at the University of Li?ge, which reveals how methylglyoxal stress ? a by-product of tumor metabolism ? promotes immunosuppression and the formation of metastases, and may contribute to resistance to immunotherapy and the progression of triple-negative cancer.

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