Sponge and sea slug partnership yields a new anticancer molecule with drug design pro

[News]

Researchers identified jorumycidine, a new hexacyclic marine alkaloid from the nudibranch Jorunna funebris and its dietary sponge, Haliclona sp., and demonstrated that it exhibits potent nanomolar cytotoxicity against multiple myeloma cells. They also proposed a new biosynthetic route involving cross-species metabolic interplay and an unusual oxazolidine ring that may help stabilize a pharmacologically important scaffold.

More... (https://www.news-medical.net/news/20260408/Sponge-and-sea-slug-partnership-yields-a-new-anticancer-molecule-with-drug-design-promise.aspx)