Chronic hypoxia upregulates RNA polymerase I, alters methylation on ribosomal RNAs

[News]

Hypoxia -- where a tissue is deprived of an adequate supply of oxygen -- is a feature inside solid cancer tumors that renders them highly invasive and resistant to treatment. Study of how cells adapt to this critical stressor, by altering their metabolism to survive in a low-oxygen environment, is important to better understand tumor growth and spread.

More... (https://www.news-medical.net/news/20210204/Chronic-hypoxia-upregulates-RNA-polymerase-I-alters-methylation-on-ribosomal-RNAs.aspx)