Research illuminates abilities of ADAR1 to ‘hyper-mutate’ tumor suppressor RNAs in le

[News]

Writing in the January 3 issue of Cancer Cell, researchers at University of California San Diego School of Medicine report that detection of "copy editing" by a stem cell enzyme called ADAR1, which is active in more than 20 tumor types, may provide a kind of molecular radar for early detection of malignancies and represent a new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation.

More... (https://www.news-medical.net/news/20190103/Research-illuminates-abilities-of-ADAR1-to-e28098hyper-mutatee28099-tumor-suppressor-RNAs-in-leukemia.aspx)