Herceptin and Joint Stiffness

[Diane6513]

Hi, I was just wondering if anyone has really bad stiff joints from Herceptin. I am on it every three weeks, but is it from that or could it be from the Taxol which I finished in March?

My Oncologist said it was from the Taxol and it will eventually go away. I'd like to know when? First thing in the morning when I get up, my lower legs and feet are like wooden pegs. No bending. And when I work out the next day in the am, my lower back is really stiff, as well as the legs. My finger joints are stiff too.

I was told because of the low dose of the Taxol I had, I would have no long lasting side effects, as I went into it with really good health. Does anyone know of anything to alleviate this?

[Nurse4u2day]

I had severe stiffness, joint and muscle pain once I started on herceptin alone. When I say severe I mean in tears severe. I was seen by a rheumatologist and based on labs they stayed I had inflammation in my body and both the rheumatologist and my oncologist said that this most likely was because of herceptin along with lingering effects of chemo. I even developed 7 trigger fingers. Was placed on routine pain meds and lots of warm showers.
The pain started to subside about two months prior to my last herceptin treatment .

[Lani]

I have read on this site that asking that the benzoyl alcohol preservative be left out of any reconstitution (dilution) of a complete vial of herceptin relieved quite a few of joint complaints and stiffness. They cannot leave the preservative out of vials partially used as someone else uses them, they don't know how long until that additional portion will be used and the preservatives need to be in mix then.

Couldn't hurt to ask to try this. As I said, quite a few here noted leaving this preservative out helped.

Hope this helps!

[valleygirl]

Yes, I agree with Lani. I get my Herceptin with just sterile water. I was in horrible pain before the change

[Nurse4u2day]

While on Herceptin alone I had tremendous bone and muscle pain. Crippling I would say. My doctors agreed it was most likely a combo of the previous treatments but that the herceptin was the straw that broke the camels back . The severe pain lasted until my 10th month of tx and slowly started to resolve .