Scientists find cause of reduced drug sensitivity in HER2-positive breast cancer [Archive]

View Full Version : Scientists find cause of reduced drug sensitivity in HER2-positive breast cancer

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10-13-2015, 04:23 AM

In the presence of the HER2 inhibitor lapatinib, the tumor suppressor molecule FOXO changes role and desensitizes HER2+ breast cancer cells to the drug, leading to relapse.

More... (http://www.medicalnewstoday.com/articles/300879.php)