Scientists examine rates of secondary mutations in biomarker genes

[News]

Many tests for predictive biomarkers in tumors focus on selected known mutations or regions (e.g. hotspot panels). In a new study, scientists at Molecular Health examined the rates of secondary mutations in known biomarker genes and their potential impact on the diagnostic reliability of specific single-nucleotide variant (SNV) biomarker testing.

More... (http://www.news-medical.net/news/20150629/Scientists-examine-rates-of-secondary-mutations-in-biomarker-genes.aspx)