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KDR
08-04-2014, 05:14 PM
http://www.nhs.uk/news/2014/07July/Pages/Aggressive-breast-cancer-protein-discovered.aspx

Cause for pause.

Karen
europa
08-04-2014, 06:24 PM
Wow....that is pretty exciting. Hope they get moving on trials
suzan w
08-04-2014, 06:24 PM
Hooray for research!!
Adriana Mangus
08-06-2014, 11:01 PM
Want it now!!!!!!
Hopeful
08-07-2014, 06:56 AM
Seventy percent of people with HER2-positive breast cancers develop resistance to Herceptin (http://www.nhs.uk/conditions/Herceptin/Pages/Introduction.aspx),

Where is this statistic coming from?

Hopeful
Mtngrl
08-13-2014, 12:06 PM
Interesting!

That's the highest estimate I've ever seen for the percentage of breast cancers that are HER-2 positive ("up to one third.") Previously I've seen 1/5 to 1/4.
KDR
08-13-2014, 03:17 PM
Hopeful, I can't speak to the content of the article. You could contact the writer, I guess. What I have learned, actually just yesterday, from a leading (has research foundation in his name) oncologist at Mt. Sinai, was that the cells that express LESS HER2 actually dodge Herceptin's radar. I thought that interesting. I am treated at Memorial, and have an integrative oncologist as well. I will ask them their thoughts on the subject.
Karen