Psoralen and Her2

[Hopeful]

Saw this on one of the news feed boards here and thought it was fascinating:

http://www.news-medical.net/news/20140218/Researchers-detail-how-psoralen-blocks-signaling-pathway-of-HER2-positive-cancers.aspx

Hopeful

[Becky]

You know what's weird? Several years ago I started eating celery. I always liked it but started loving it. MDH asked me not to put it in everything as he prefers not to have it in every salad. I find this odd. Oh well, at least it has something in it. Maybe the body naturally tells you what you need.

[Hopeful]

Maybe the body naturally tells you what you need.

Becky, I am a big believer in this.

Hopeful

[cienna]

Interesting article. Thanks for sharing.

[Lani]

open access full article
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0088983

[littledute]

I found this exciting news as this drug (psoralen) breaks through the inner core by disrupting DNA replication and causing cell death when activated by an energy source such as UV light.
“Cancer drugs can recognize HER2 receptors when they are outside of the cell, but they don’t recognize the truncated version inside the cell nucleus. They have shown that psoralen is effective in targeting this other form of HER2 that is resistant to current HER2-targeted therapies.” I hope they have some clinical trails soon! They need to figure out how to get the UV light to the inner core of the HER2 positive cancer cell!!!