how long did kadcyla (tdm1) work for you?

[debsing]

Just had my second round of kadcyla and was hoping those of you who took this could tell me how long it has lasted?

[KDR]

1.5 years. NED. I did kickstart the trial with Perjeta and Taxol with T-DM1 and was NED on first cycle. It was grueling. Some hazardous side effects. Then, we stopped Taxol on the third month or so, and continued with Perjeta and T-DM1. Was NED 1.5 years, then a tiny spot recurred on my liver. Had that ablated (see signature). NED again, on Herceptin alone. YOU CAN DO THIS!

Karen

[debsing]

I hope I can get a long run until the next great drug! Thank you!

[Kathy T]

Stable for 4 years and counting.....with TDM1.
Kathy T

[debsing]

Ahh! That's wonderful!

[debsing]

I'm taking milk thistle to try and help support my liver, since its been through a lot between tumors and this treatment. My oncologist told me kadcyla can be hard on the liver. Anyone else try milk thistle?

[KDR]

Milk thistle behaves differently on individuals. I know someone who had very negative side effects, which blew my balloon because I had just purchased some for myself. Also, it's not quite clear how the MT affects chemotherapy if directly needed in the liver (if you have liver mets). Check with your doctor, I guess, and be sure it's o.k.

Kathy T--that is fabulous...could you tell us where in the body you were affected and if you have side effects? Keep going!

Karen

[debsing]

I love love love your picture kdr! I dream of Jeannie has always been a favorite!

[Kathy T]

Mainly bone met, possibly lung, but not bx. And no issues in the last 10 years since I became stage 4. The side effects are typical, low platelets, elevated liver functions, etc. it has been a great drug for me.
Kathy T