Does IV Navebine cross the BB Barrier

[dchips1]

Was wondering if navelbine crosses blood brain barrier?
Mixed results online with my research'

Thank you and prayers for all

Darita

[CarolineC]

Darita,

Maybe you've already gotten this info from another source. This is from bccancer.bc.ca-although from 2008-
http://www.bccancer.bc.ca/NR/rdonlyres/7267649C-7408-497B-AF85-0EBE7CA6E8F5/28176/Vinorelbinemonograph1Mar08.pdf

I almost did Navelbine last year but decided to do Docetaxel-http://www.bccancer.bc.ca/NR/rdonlyres/A169EECB-85A4-4F6E-A8A3-38C95B2DB8E1/63146/docetaxel_monograph_1Apr2013_formatted.pdf- it says this chemo crosses the BBB at very low levels.

Don't know if this helps you.